M5525
4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯
≥98%, powder
别名:
N-琥珀酰亚胺基4-(马来酰亚胺基甲基)环己烷羧酸酯, SMCC
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关于此项目
经验公式（希尔记法）:
C16H18N2O6
化学文摘社编号:
分子量:
334.32
UNSPSC Code:
12352103
NACRES:
NC.07
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1555271
产品名称
4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯, ≥98%, powder
InChI
1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
SMILES string
O=C(ON1C(CCC1=O)=O)C2CCC(CN3C(C=CC3=O)=O)CC2
InChI key
JJAHTWIKCUJRDK-UHFFFAOYSA-N
assay
≥98%
form
powder
reaction suitability
reagent type: linker
mp
180-182 °C (lit.)
solubility
chloroform: 50 mg/mL
DMF: soluble
functional group
NHS ester
shipped in
wet ice
storage temp.
−20°C
Quality Level
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Application
4-（N-马来酰亚胺基甲基）环己烷羧酸 N-羟基琥珀酰亚胺酯（SMCC）可用于制备酶免疫结合物和半抗原载体分子结合物。它已用于将肽序列与氨基进行偶联。
General description
4-（N-马来酰亚胺基甲基）环己烷羧酸 N-羟基琥珀酰亚胺酯（SMCC）是一种异双功能交联剂，其包含一个具有胺和巯基反应性的延长间隔基。它通常首先通过酰胺键（pH7.5（6.5-8.5）缓冲）与含有伯胺的分子进行偶联。第二次偶联通过硫醚键（pH6.8（6.5-7.0）缓冲）与含有游离巯基的分子进行特异性偶联。SMCC包含九个原子连接子。与芳族间隔基相比，延伸的脂族间隔基可在偶联之前稳定马来酰亚胺。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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