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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
orange to red
溶解性
H2O: 10 mg/mL, clear
储存温度
2-8°C
SMILES字符串
CN(C1=C(S/2)C=CC=C1)C2=C3C(N(CC)/C(S\3)=C/C4=[N+](CC)C=CC=C4)=O.[Cl-]
InChI
1S/C21H22N3OS2.ClH/c1-4-23-13-9-8-10-15(23)14-18-24(5-2)20(25)19(27-18)21-22(3)16-11-6-7-12-17(16)26-21;/h6-14H,4-5H2,1-3H3;1H/q+1;/p-1/b21-19+;
InChI key
VSKYOTRJSLYFHX-UXJRWBAGSA-M
生化/生理作用
MKT-077 是线粒体 hsp70 家族成员致死蛋白 (mot-2) n 的抑制剂;它导致癌细胞选择性死亡。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种:
Biology open, 6(4), 481-488 (2017-03-16)
Earlier studies suggested that
American journal of physiology. Cell physiology, 318(2), C289-C303 (2019-12-05)
Glucose-regulated protein 75 (GRP75) was first characterized in mammals as a heat shock protein-70 (HSP70) family stress chaperone based on its sequence homology. Extensive studies in mammals showed that GRP75 is induced by various stressors such as glucose deprivation, oxidative
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Zika virus (ZIKV) is a historically neglected mosquito-borne flavivirus that has caused recent epidemics in the western hemisphere. ZIKV has been associated with severe symptoms including infant microcephaly and Guillain-Barré syndrome, stimulating interest in understanding factors governing ZIKV infection. Heat
BMC cancer, 19(1), 258-258 (2019-03-25)
The oncoprotein MYC has the dual capacity to drive cell cycle progression or induce apoptosis, depending on the cellular context. BAG1 was previously identified as a transcriptional target of MYC that functions as a critical determinant of this cell fate
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(12), 14611-14624 (2019-11-07)
Plasmodium falciparum is the most lethal of human-infective malaria parasites. A hallmark of P. falciparum malaria is extensive remodeling of host erythrocytes by the parasite, which facilitates the development of virulence properties such as host cell adhesion to the endothelial
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