M5162
3-吗啉丙磺酸
BioXtra, ≥99.5% (titration)
别名:
3-(N-吗啉基)丙磺酸, 4-吗啉丙磺酸
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经验公式（希尔记法）:
C7H15NO4S
化学文摘社编号:
分子量:
209.26
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
214-478-5
Beilstein/REAXYS Number:
1106776
MDL number:
InChI key
DVLFYONBTKHTER-UHFFFAOYSA-N
InChI
1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
SMILES string
OS(=O)(=O)CCCN1CCOCC1
grade
reagent grade
sterility
non-sterile
product line
BioXtra
assay
≥99.5% (titration)
form
powder
technique(s)
cell culture | mammalian: suitable, electrophoresis: suitable
impurities
Insoluble matter, passes filter test
ign. residue (900°C)
≤0.1% (as SO4)
loss
≤1% loss on drying, 110°C
pH
2.5-4.0 (1 M in H2O)
useful pH range
6.5-7.9
pKa (25 °C)
7.2
solubility
H2O: 1 M, clear, colorless
anion traces
chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.005%
cation traces
Al: ≤0.0005%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, Na: ≤0.005%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%
absorption
≤0.015 at 280 in H2O at 1 M, ≤0.020 at 260 in H2O at 1 M
λ
1 M in H2O
suitability
suitable for electrophoresis
Quality Level
application(s)
diagnostic assay manufacturing
storage temp.
room temp
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General description
MOPS is a morpholino propanesulfonic acid, a structural analog to MES, the ethanesulfonic acid (first introduced by Good et al.), developed to meet the following criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pK a with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range and reasonably easily synthesized.
Application
- 微骨穿孔术通过刺激牙周韧带细胞周期来加速正畸牙齿移动。: 该研究探索了正畸环境下使用MOPS缓冲液来促进牙齿加速运动的用途，增强了治疗′功效和患者恢复结果（Sugimori et al., 2018）。
- 壳聚糖促进的人亚硫酸盐氧化酶的直接电化学。: 研究展示了MOPS缓冲液′在电化学研究过程中维持酶稳定性和活性的关键作用 ，提供了有关生物化学应用的见解（Kalimuthu et al., 2017）。
- 通过DF-PAGE蛋白组学分析用非SDS聚丙烯酰胺凝胶电泳进行肽分级分离 。: 该研究在新型电泳技术中利用MOPS缓冲液来改善肽的分离度和分离，该技术有助于蛋白组学分析 （Ramos et al., 2012）。
Features and Benefits
Features:
- Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
- Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
- M-Clarity™ Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity™ Program
- Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
- Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
- Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
- Site quality assessment
- ISO 9001 certificate
- Detailed product specifications
- Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
- Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
- Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
- Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
- Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
- Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
- Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.
Other Notes
使用 MOPS 规格表可以非常轻松比较 MOPS 产品规格。
Legal Information
M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Junji Suzuki et al.
Nature communications, 5, 4153-4153 (2014-06-14)
The endoplasmic reticulum (ER) and mitochondria accumulate Ca(2+) within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca(2+) has proven to be difficult. Here we describe a family of genetically encoded Ca(2+) indicators, named calcium-measuring
Sewa Rijal et al.
Blood, 125(18), 2815-2824 (2015-03-05)
Phosphoinositide signaling regulates diverse cellular functions. Phosphoinositide-3 kinase (PI3K) generates PtdIns(3,4,5)P3 and PtdIns(3,4)P2, leading to the activation of proliferative and anti-apoptotic signaling pathways. Termination of phosphoinositide signaling requires hydrolysis of inositol ring phosphate groups through the actions of PtdIns(3,4,5)P3 3-phosphatase
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
Y S L Lee et al.
Human reproduction (Oxford, England), 30(3), 543-552 (2015-01-09)
What is the relationship between cleavage stage embryo kinetics, blastocyst metabolism and subsequent embryo viability? Embryos cleaving faster at the first cleavage division resulted in blastocysts with a larger inner cell mass (ICM), higher glucose consumption, lower glycolytic rate, higher
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