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Merck
CN

M5005

Sigma-Aldrich

氯化锰 四水合物

BioReagent, suitable for insect cell culture

别名:

Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O

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About This Item

线性分子式:
MnCl2 · 4H2O
CAS号:
分子量:
197.91
EC 号:
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:
NACRES:
NA.28
方案:
≥99% (by AgNO3, titration)

产品线

BioReagent

质量水平

方案

≥99% (by AgNO3, titration)

技术

cell culture | insect: suitable

mp

58 °C (lit.)

SMILES字符串

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

InChI key

CNFDGXZLMLFIJV-UHFFFAOYSA-L

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应用

四水合氯化锰 (II) 已被用于:
  • 作为真菌完全培养基中的微量元素
  • 作为耳蜗器官型培养的培养基中的补充
  • 测定其对小鼠单纯疱疹病毒-1 (HSV-1)、水泡性口炎病毒 (VSV) 和痘苗病毒的体内抗病毒活性

生化/生理作用

锰是哺乳动物组织中必需的和含量丰富的金属之一。在发育、神经元功能、免疫调节、生殖和抗氧化防御等生理过程中起关键作用。作为辅助因子,调节酶的活性,如氧化还原酶、异构酶、转移酶、连接酶、裂合酶和水解酶,参与固有免疫。

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

靶器官

Brain

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

闪点(°F)

does not flash

闪点(°C)

does not flash

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Salidroside protects inner ear hair cells and spiral ganglion neurons from manganese exposure by regulating ROS levels and inhibiting Apoptosis
Ding X, et al.
Toxicology Letters, 310, 51-60 (2019)
manganese Increases the Sensitivity of the cgas-sting Pathway for Double-stranded Dna and Is Required for the Host Defense against Dna Viruses.
Wang C, et al.
Immunity, 48(4), 675-687 (2018)
Weilong Wang et al.
Toxicology letters, 279, 77-86 (2017-08-06)
Manganese (Mn) is an indispensable cofactor for many enzymes and a basic factor for many reproductive and metabolic pathways. However, exposure to high concentrations of Mn can result in deleterious effects on the central nervous system and peripheral nerves, including
Xuerui Ding et al.
Toxicology letters, 310, 51-60 (2019-04-17)
Manganese (Mn) is an essential cofactor for many enzymes and thus plays an important role in normal growth and development. However, persistent exposure to high Mn concentrations can result in deleterious effects on not only the central nervous system but
Christopher J Harbort et al.
STAR protocols, 1(3), 100226-100226 (2020-12-31)
We present a gnotobiotic system for microbiota reconstitution on Arabidopsis thaliana under contrasting iron availability. This system induces iron starvation in plants by providing an unavailable form, mimicking conditions in alkaline soils. Inoculation of taxonomically diverse bacteria reconstitutes plants with

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