M4879
3-O-甲基-D-吡喃葡萄糖
≥98% (GC)
别名:
3-O-甲基葡萄糖, 甲基葡萄糖
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关于此项目
经验公式（希尔记法）:
C7H14O6
化学文摘社编号:
分子量:
194.18
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
236-197-7
MDL number:
产品名称
3-O-甲基-D-吡喃葡萄糖, ≥98% (GC)
InChI key
SCBBSJMAPKXHAH-OVHBTUCOSA-N
InChI
1S/C7H14O6/c1-12-6-4(9)3(2-8)13-7(11)5(6)10/h3-11H,2H2,1H3/t3-,4-,5-,6+,7+/m1/s1
SMILES string
CO[C@@H]1[C@@H](O)[C@@H](O)O[C@H](CO)[C@H]1O
assay
≥98% (GC)
form
powder
optical activity
[α]25/D 55 to 57 °, c = 1% (w/v) in water + trace NH4OH
technique(s)
gas chromatography (GC): suitable
mp
167-169 °C (lit.)
solubility
water: 50 mg/mL, clear to slightly hazy, colorless
Quality Level
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Application
Varying concentrations of 3-O-methyl-D-glucopyranose were used to measure responses of jejunal and ileal short circuit currents to determine maximal transport capacity and carrier affinity in a study to assess intestinal glucose transport in rats with diabetes mellitus. It has also been used in a study to investigate nonmetabolizable glucose analogues and ornithine decarboxylase expression in LLC-PK1 cells.
General description
3-O-Methyl-D-glucopyranose is a passive carrier-mediated transported glucose analogue.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
R N Fedorak et al.
Canadian journal of physiology and pharmacology, 69(8), 1143-1148 (1991-08-01)
Chronic diabetes enhances intestinal absorption of glucose and induces hyperphagia. We examined the enhanced intestinal absorption of glucose in ad libitum-fed rats with streptozocin-induced diabetes mellitus and compared these results with those obtained from pair-fed diabetic animals. Maximal transport capacity
Asaf Miller et al.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 19(1), 37-42 (2017-02-22)
To evaluate the effect of exogenous glucagonlike peptide-1 (GLP-1) on small intestinal glucose absorption and blood glucose concentrations during critical illness. A prospective, blinded, placebo-controlled, cross-over, randomised trial in a mixed medical-surgical adult intensive care unit, with 12 mechanically ventilated
D W Lundgren et al.
The American journal of physiology, 259(4 Pt 1), C647-C653 (1990-10-01)
This report examines the effect of nonmetabolizable glucose analogues on ornithine decarboxylase (ODC) activity in LLC-PK1 cells. The addition of Na(+)-dependent cotransported glucose analogues, 1-O-methyl-alpha-D-glucopyranoside (alpha-MDG) and 1-O-methyl-beta-D-glucopyranoside, to Earle's balanced salt solution minus glucose (EBSS-G) increased ODC activity five-
Anna E Di Bartolomeo et al.
Critical care (London, England), 16(5), R167-R167 (2012-09-19)
Studies in the critically ill that evaluate intragastric and post-pyloric delivery of nutrient have yielded conflicting data. A limitation of these studies is that the influence in the route of feeding on glucose absorption and glycaemia has not been determined.
Nam Q Nguyen et al.
Obesity surgery, 26(1), 77-84 (2015-05-20)
The aim was to determine the effects of fat and protein preloads on pouch emptying (PE), caecal arrival time (CAT), glucose absorption, blood glucose (BSL), gut hormones, haemodynamics and gastrointestinal (GI) symptoms in subjects who had undergone Roux-en-Y gastric bypass
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