推荐产品
质量水平
检测方案
≥99%
形式
powder
mp
212-215 °C (dec.) (lit.)
溶解性
water: 25 mg/mL, clear, colorless
SMILES字符串
CC1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N=C1N
InChI
1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1
InChI key
ZAYHVCMSTBRABG-JXOAFFINSA-N
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一般描述
5-甲基胞苷是 大肠杆菌 中 RNA 的成分。它存在于植物、动物和细菌来源的 RNA 中。它是存在于转移 RNA (tRNA) 中的 C 衍生物之一。
应用
5-甲基胞苷用于 DNA 甲基化过程（表观遗传学）的研究。
使用 5-甲基胞苷作为反相高效液相色谱法 (RP-HPLC) 校准曲线的标准品。
生化/生理作用
5-甲基胞苷是一种烷基化的嘧啶，在核酸的 α-螺旋和 β-螺旋中具有重要的堆积增强作用，提高了核酸的解链温度，改善了热稳定性，从而达到稳定结构的目的。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Leonidas Chouliaras et al.
Neurobiology of aging, 33(8), 1672-1681 (2011-07-19)
Aberrant DNA methylation patterns have been linked to molecular and cellular alterations in the aging brain. Caloric restriction (CR) and upregulation of antioxidants have been proposed as interventions to prevent or delay age-related brain pathology. Previously, we have shown in
DNA Methyltransferases - Role and Function, 30-30 (2016)
Advances in Carbohydrate Chemistry, Volume 14, 291-291 (1959)
Marija Kojic et al.
Nature communications, 9(1), 3195-3195 (2018-08-12)
Cerebellar ataxias are severe neurodegenerative disorders with an early onset and progressive and inexorable course of the disease. Here, we report a single point mutation in the gene encoding Elongator complex subunit 6 causing Purkinje neuron degeneration and an ataxia-like
Maria Beatrice Bitonti et al.
Journal of experimental botany, 53(371), 1047-1054 (2002-04-25)
Chromatin organization, nuclear DNA methylation and endogenous zeatin localization were investigated in shoot apical meristems (SAM) during juvenile and adult phases of peach (Prunus persica (L.) Batsch). The aim was to examine the extent to which these parameters could discriminate
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