M4199
Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse
lyophilized powder
别名:
MOG (40-54)
产品名称
Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse, lyophilized powder
biological source
rat
assay
≥97% (HPLC)
form
lyophilized powder
color
white
solubility
deionized water: soluble
storage temp.
−20°C
Quality Level
Gene Information
mouse ... Mog(17441)
rat ... Mog(24558)
Biochem/physiol Actions
The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.
Other Notes
Lyophilized from 0.1% TFA in H2O
Physical form
Lyophilized from 0.1% aqueous TFA.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Oligodendrocyte myelin glycoprotein (OMgp) in rat hippocampus is depleted by chronic ethanol consumption.
Okamoto H
Neuroscience Letters (2006)
Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice
Cecile Delarasse
Immunology (2013)
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