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Merck
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安全信息

M4199

Sigma-Aldrich

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

lyophilized powder

别名:

MOG (40-54)

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About This Item

经验公式(希尔记法):
C84H127N27O21
分子量:
1851.08
UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

rat

质量水平

检测方案

≥97% (HPLC)

形式

lyophilized powder

颜色

white

溶解性

deionized water: soluble

UniProt登记号

储存温度

−20°C

基因信息

mouse ... Mog(17441)
rat ... Mog(24558)

相关类别

Amino Acid Sequence

Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly

生化/生理作用

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

外形

Lyophilized from 0.1% aqueous TFA.

其他说明

Lyophilized from 0.1% TFA in H2O

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Oligodendrocyte myelin glycoprotein (OMgp) in rat hippocampus is depleted by chronic ethanol consumption.
Okamoto H
Neuroscience Letters (2006)
Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice
Cecile Delarasse
Immunology (2013)

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