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Merck
CN

M4154

Sigma-Aldrich

β-N-Methylamino-L-alanine hydrochloride

别名:

L-BMAA

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About This Item

经验公式(希尔记法):
C4H10N2O2 · HCl
CAS号:
分子量:
154.60
MDL编号:
UNSPSC代码:
12352200

储存温度

2-8°C

SMILES字符串

CNCC(N)C(O)=O

生化/生理作用

Neuroexcitotoxic amino acid; may be involved in Guam amyotrophic lateral sclerosis

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Oliver Okle et al.
Toxicology and applied pharmacology, 270(1), 9-15 (2013-04-18)
The cyanobacterially produced neurotoxin beta-N-methylamino-l-alanine (BMAA) is thought to induce amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS/PDC)-like symptoms. However, its mechanism of action and its pathway of intoxication are yet unknown. In vivo animal models suitable for investigating the neurotoxic effect
Elisabeth J Faassen et al.
PloS one, 7(5), e36667-e36667 (2012-05-10)
The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) has been considered a serious health threat because of its putative role in multiple neurodegenerative diseases. First reports on BMAA concentrations in cyanobacteria were alarming: nearly all cyanobacteria were assumed to contain high BMAA concentrations
J S Metcalf et al.
Chemosphere, 90(2), 835-839 (2012-11-06)
The Lesser Flamingo (Phoeniconaias minor) is known to use cyanobacteria (primarily Arthrospira) as a major food source in the East African Rift Valley lakes. Periodically, mass mortalities have occurred, associated with the cyanobacterial toxins (cyanotoxins), microcystins and anatoxin-a. Deposition of
Oskar Karlsson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 130(2), 391-404 (2012-08-09)
The cyanobacterial toxin β-N-methylamino-L-alanine (BMAA) has been proposed to contribute to neurodegenerative disease. We have previously reported a selective uptake of BMAA in the mouse neonatal hippocampus and that exposure during the neonatal period causes learning and memory impairments in
The emerging science of BMAA: do cyanobacteria contribute to neurodegenerative disease?
Wendee Holtcamp
Environmental health perspectives, 120(3), A110-A116 (2012-03-03)

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