推荐产品
质量水平
检测方案
≥98% (HPLC)
形式
powder
溶解性
methanol: 1 mg/mL, clear, very light yellow
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
2-8°C
SMILES字符串
COc1c(O)cc2Oc3cc(O)c(C\C=C(\C)C)c(O)c3C(=O)c2c1C\C=C(/C)C
InChI
1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3
InChI key
GNRIZKKCNOBBMO-UHFFFAOYSA-N
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一般描述
α-倒捻子素(α-MG)是丰富的植物化学成分，可从山竹获得。它是四氧二异戊烯化氧杂蒽酮。α-MG分子的化学结构为1,3,6-三羟-7-甲氧基-2,8-双(3-甲基-2-丁烯基)- 9H-氧杂蒽-9-酮。
应用
α-倒捻子素已被用于：
- 研究对氧化应激介导的视网膜细胞死亡的保护作用
- 研究其作为抗遗传毒性试剂在DNA氧化损伤保护中的作用
- 了解其抵御表皮葡萄球菌 RP62A的抗菌活性
生化/生理作用
α-倒捻子素在体外和体内研究中均展现出各种药理性质。 这些特性包括抗菌、抗癌、抗糖尿病、神经保护、护肝和抗炎。
从山竹（ 山竹 ）中分离得到的黄酮类衍生物。抗氧化和抗炎。研究表明，α-山竹素通过线粒体途径诱导细胞凋亡，减少细胞增殖，抑制肿瘤的发生。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Aungkana Krajarng et al.
Research in veterinary science, 93(2), 788-794 (2012-02-22)
Osteosarcoma is the most frequently diagnosed primary bone tumor in dog. Since chemotherapeutics are quite limited due to high cost and severe toxicity, therefore, the ultimate goal is to discover cost-effective therapeutics with less toxicity. We have studied the effect
Murugesan Sivaranjani et al.
Frontiers in microbiology, 10, 150-150 (2019-02-23)
Background: Alpha-mangostin (α-MG) is a natural xanthone reported to exhibit rapid bactericidal activity against Gram-positive bacteria, and may therefore have potential clinical application in healthcare sectors. This study sought to identify the impact of α-MG on Staphylococcus epidermidis RP62A through
alpha-Mangostin from Garcinia mangostana Linn: an updated review of its pharmacological properties
Ibrahim MY, et al.,
Arabian Journal of Chemistry, 317-329 (2016)
Xiaofang Quan et al.
PloS one, 7(3), e33376-e33376 (2012-03-20)
α-Mangostin, isolated from the hulls of Garcinia mangostana L., was found to have in vitro cytotoxicity against 3T3-L1 cells as well as inhibiting fatty acid synthase (FAS, EC 2.3.1.85). Our studies showed that the cytotoxicity of α-mangostin with IC(50) value
Ali Ghasemzadeh et al.
Molecules (Basel, Switzerland), 23(8) (2018-07-26)
Since α-mangostin in mangosteen fruits was reported to be the main compound able to provide natural antioxidants, the microwave-assisted extraction process to obtain high-quality α-mangostin from mangosteen pericarp (Garcinia mangostana L.) was optimized using a central composite design and response
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