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Merck
CN

M3633

4-甲基伞形酮基β-D-葡萄糖苷

β-glucosidase substrate, fluorogenic, ≥99% (HPLC), powder

别名:

MUD

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关于此项目

经验公式（希尔记法）:
C16H18O8
化学文摘社编号:
18997-57-4
分子量:
338.31
NACRES:
NA.32
PubChem Substance ID:
24896859
UNSPSC Code:
12352204
EC Number:
242-736-7
MDL number:
MFCD00063694
Beilstein/REAXYS Number:
94672

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产品名称

4-甲基伞形酮基β-D-葡萄糖苷, β-glucosidase substrate

InChI key

YUDPTGPSBJVHCN-YMILTQATSA-N

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1

SMILES string

CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

assay

≥99% (HPLC)

form

powder

solubility

DMF: 50 mg/mL, clear, colorless to faintly yellow

fluorescence

λex 316 nm; λem 372 nm (pH 9.1), λex 360 nm; λem 449 nm (Reaction product)

storage temp.

−20°C

Quality Level

200

Application

4-甲基伞形酮基β-D-葡萄糖苷可用来作为以下反应的底物：
  • 原发性海马神经元富含溶菌酶部分葡糖神经酰胺酶β 酶活性分析
  • 酵母发酵过程中β-葡萄糖苷酶分析
  • 巨噬细胞细胞系(RAW)中的葡萄糖脑苷脂酶1（GBA1）-相关葡萄糖苷酶活性分析

Biochem/physiol Actions

4-甲基伞形酮基β-D-葡萄糖苷是一种合成糖苷酶底物。它可用作来自肠球菌的葡萄糖苷酶底物。

Other Notes

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000506151
0000506173
0000506164
0000506163
0000506163

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Assessing microbial safety of drinking water improving approaches and methods: Improving approaches and methods, 253-253 (2003)
HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution
Tol MJ, et al.
Autophagy, 14(3), 437-449 (2018)
Samantha G Scharenberg et al.
Nature communications, 11(1), 3327-3327 (2020-07-06)
Gaucher disease is a lysosomal storage disorder caused by insufficient glucocerebrosidase activity. Its hallmark manifestations are attributed to infiltration and inflammation by macrophages. Current therapies for Gaucher disease include life-long intravenous administration of recombinant glucocerebrosidase and orally-available glucosylceramide synthase inhibitors.
A Rashidi et al.
Bone marrow transplantation, 51(12), 1561-1564 (2016-08-16)
Post-transplant cyclophosphamide (PT-Cy) is the backbone of GvHD prophylaxis following haploidentical hematopoietic cell transplantation (haplo-HCT). PT-Cy has also been used in matched related (MRD) and unrelated (MUD) settings. It is not known whether outcomes are similar between haplo-HCT and MRD/MUD
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Probiotics and Human Health

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

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Product Information Sheet - M3633

Product Information Sheet

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