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Merck
CN

M3013

Sigma-Aldrich

β-甲基巴豆酰基辅酶A 锂盐

≥90%

别名:

反式-3-甲基-2-丁烯酰基辅酶A

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About This Item

经验公式(希尔记法):
C26H42N7O17P3S
分子量:
849.63
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

质量水平

检测方案

≥90%

储存温度

−20°C

SMILES字符串

[Li].C\C(C)=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)n2cnc3c(N)ncnc23

InChI

1S/C26H42N7O17P3S.Li.H/c1-14(2)9-17(35)54-8-7-28-16(34)5-6-29-24(38)21(37)26(3,4)11-47-53(44,45)50-52(42,43)46-10-15-20(49-51(39,40)41)19(36)25(48-15)33-13-32-18-22(27)30-12-31-23(18)33;;/h9,12-13,15,19-21,25,36-37H,5-8,10-11H2,1-4H3,(H,28,34)(H,29,38)(H,42,43)(H,44,45)(H2,27,30,31)(H2,39,40,41);;

InChI key

LTOKXDRORBIJJG-UHFFFAOYSA-N

应用

辅酶A功能是作为酰基载体,乙酰-辅酶A。β-甲基巴豆酰基辅酶A可用作研究β-甲基巴豆酰基辅酶A羧化酶(MCCase)的特异性和动力学的底物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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X. Wang et al.
Plant physiology, 108(3), 1133-1139 (1995-07-01)
Regulation of the expression of the gene(s) coding for the 78-kD, biotin-containing subunit of [beta]-methylcrotonyl-coenzyme A carboxylase (MCCase) was investigated in different organs of tomato (Lycopersicon esculantus) plants. The specific activity of MCCase is highest in extracts from roots, followed
S Aubert et al.
FEBS letters, 383(3), 175-180 (1996-04-01)
Induction of beta-methylcrotonyl-coenzyme A carboxylase (MCCase) activity was observed during carbohydrate starvation in sycamore cells. In mitochondria isolated from starved cells, we noticed a marked accumulation of the biotinylated subunit of MCCase, of which the apparent molecular weight of 74000
B Wolf et al.
Enzyme, 24(5), 302-306 (1979-01-01)
At least one arginine residue is essential for substrate binding in or near the active sites of propionyl CoA carboxylase (PCC) and beta-methylcrotonyl CoA carboxylase (beta MCC) in cultured human fibroblasts. This conclusion is based on studies of enzyme inhibition
Kiyoung Kim et al.
Life (Basel, Switzerland), 11(1) (2021-01-23)
Although mitochondrial dysfunction is associated with the development and progression of diabetic nephropathy (DN), its mechanisms are poorly understood, and it remains debatable whether mitochondrial morphological change is a cause of DN. In this study, a Drosophila DN model was
Elma Zaganjor et al.
Cell reports, 36(2), 109345-109345 (2021-07-15)
Upon nutrient stimulation, pre-adipocytes undergo differentiation to transform into mature adipocytes capable of storing nutrients as fat. We profiled cellular metabolite consumption to identify early metabolic drivers of adipocyte differentiation. We find that adipocyte differentiation raises the uptake and consumption

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