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质量水平
检测方案
≥94% (TLC)
形式
liquid
官能团
ester
脂质类型
neutral glycerides
运输
ambient
储存温度
−20°C
SMILES字符串
[H]C(CO)(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO
InChI
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChI key
UPWGQKDVAURUGE-KTKRTIGZSA-N
生化/生理作用
2-单油精（2-油酰甘油）可用作GPR119激动剂，调节GLP-1的释放。2-单油精可用于区分和研究单酰基甘油脂肪酶的动力学。
包装
在氩气下包装。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Katrine B Hansen et al.
The Journal of clinical endocrinology and metabolism, 96(9), E1409-E1417 (2011-07-23)
Dietary fat is thought to stimulate release of incretin hormones via activation of fatty acid receptors in the intestine. However, dietary fat (triacylglycerol) is digested to 2-monoacylglycerol and fatty acids. Activation of G protein-coupled receptor 119 (GPR119) stimulates glucagon-like peptide-1
Christopher J Fowler et al.
Biochemical pharmacology, 69(8), 1241-1245 (2005-03-30)
In the present study, the abilities of cyclooxygenated derivatives of 1-arachidonoylglycerol and related compounds to prevent the metabolism of [3H]2-oleoylglycerol and [3H]anandamide by cytosolic and membrane fractions, respectively, have been investigated. For each compound, nine concentrations (range 0.2-100 microM) were
Verena Hiebl et al.
Biological procedures online, 22, 7-7 (2020-04-21)
The human Caco-2 cell line is a common in vitro model of the intestinal epithelial barrier. As the intestine is a major interface in cholesterol turnover and represents a non-biliary pathway for cholesterol excretion, Caco-2 cells are also a valuable
Dong Cheng et al.
The Journal of biological chemistry, 283(44), 29802-29811 (2008-09-05)
Acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1) is one of the four intestinal membrane bound acyltransferases implicated in dietary fat absorption. Recently, it was found that, in addition to acylating diacylglycerol (DAG), DGAT1 also possesses robust enzymatic activity for acylating monoacylglycerol
S Vandevoorde et al.
British journal of pharmacology, 150(2), 186-191 (2006-12-05)
Two compounds, URB602 and URB754, have been reported in the literature to be selective inhibitors of monoacylglycerol lipase, although a recent study has questioned their ability to prevent 2-arachidonoyl hydrolysis by brain homogenates and cerebellar membranes. In the present study
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