M2786
3-马来酰亚胺基苯甲酸 N -羟基琥珀酰亚胺酯
crystalline
别名:
MBS
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关于此项目
经验公式（希尔记法）:
C15H10N2O6
化学文摘社编号:
分子量:
314.25
UNSPSC Code:
12352108
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1505254
产品名称
3-马来酰亚胺基苯甲酸 N -羟基琥珀酰亚胺酯, crystalline
InChI key
LLXVXPPXELIDGQ-UHFFFAOYSA-N
SMILES string
O=C1CCC(N1OC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O)=O
InChI
1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
form
crystalline
reaction suitability
reagent type: cross-linking reagent
mp
175-177 °C (lit.)
solubility
DMSO: ≤20 mg/mL
functional group
NHS ester
maleimide
storage temp.
−20°C
Quality Level
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Application
3-马来酰亚胺基苯甲酸 N-琥珀酰亚胺酯已被用于：
- 拟南芥中花粉的固定
- 作为MS培养基的成分使桉树根毛中的纤维状肌动蛋白保持稳定
- 兰州百合纤维状肌动蛋白标记的花粉管的固定
3-马来酰亚胺基苯甲酸 N-羟基琥珀酰亚胺酯（MBS）已用作蛋白质交联剂。它已被用于稳定植物组织样品中的肌动蛋白丝。
对伯胺和巯基具有反应性的双异官能化交联剂。通常，初始反应在 pH 为 7.0 时，通过酰胺键偶联至含伯胺的分子，然后在相同 pH 通过硫醚偶联至含巯基的化合物。用于制备酶免疫交联剂和半抗原载体分子偶联物。
Biochem/physiol Actions
3-马来酰亚胺基苯甲酸N-琥珀酰亚胺可用作固定剂，用于保持花粉管纤维状肌动蛋白的分布。它用于花粉管时产生的损伤较少。
General description
可能需要在偶联缓冲液中加入溶剂（至少5%）以维持溶解度
Other Notes
芳基马来酰亚胺比烷基马来酰亚胺连接基更不稳定。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Visualization of Actin Organization and Quantification in Fixed Arabidopsis Pollen Grains and Tubes
Qu X, et al.
Bio-protocol, 10(01), 204-211 (2020)
Opioids Binding Mu and Delta Receptors Exhibit Diverse Efficacy in the Activation of Gi2and Gx/z Transducer Proteins in Mouse Periaqueductal Gray Matter.
Garzon J
Journal of Pharmacology and Experimental Therapeutics, 281, 549-557 (1997)
Andrii Slonchak et al.
BMC genomics, 20(1), 474-474 (2019-06-12)
Extracellular vesicles (EVs) are small membrane vesicles secreted by the cells that mediate intercellular transfer of molecules and contribute to transduction of various signals. Viral infection and action of pro-inflammatory cytokines has been shown to alter molecular composition of EV
Actin organization during Eucalyptus root hair development and its response to fungal hypaphorine
Dauphin A, et al.
Plant Biology (Stuttgart, Germany), 8(02), 204-211 (2006)
A Dauphin et al.
Plant biology (Stuttgart, Germany), 8(2), 204-211 (2006-03-21)
The fungus Pisolithus microcarpus establishes an ectomycorrhiza with Eucalyptus globulus. This symbiosis involves a fungal synthesis and secretion of hypaphorine, an indolic compound. Previous studies have shown that hypaphorine induces an alteration in the actin cytoskeleton of elongating root hairs
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