M2692
MK-886 sodium salt hydrate
>98% (HPLC)
别名:
3-[3-tert-Butylthio-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethylpropionic acid, sodium salt hydrate
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关于此项目
经验公式（希尔记法）:
C27H33NO2ClSNa · xH2O
化学文摘社编号:
分子量:
494.06 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C27H34ClNO2S.Na.H2O/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18;;/h8-14,17H,15-16H2,1-7H3,(H,30,31);;1H2/q;+1;/p-1
SMILES string
O.[Na+].CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C([O-])=O)c(SC(C)(C)C)c2c1
InChI key
APMAGPLTTCSTMM-UHFFFAOYSA-M
assay
>98% (HPLC)
color
white
solubility
DMSO: 32 mg/mL, H2O: insoluble
storage temp.
2-8°C
Biochem/physiol Actions
Potent and specific inhibitor of leukotriene biosynthesis.
Features and Benefits
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Chen-Hsuan Wang et al.
Brain research bulletin, 79(3-4), 169-176 (2009-05-12)
Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Results showed that early induction (at 6h of
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