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Merck
CN

M2692

Sigma-Aldrich

MK-886 sodium salt hydrate

>98% (HPLC)

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别名:
3-[3-tert-Butylthio-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethylpropionic acid, sodium salt hydrate
经验公式(希尔记法):
C27H33NO2ClSNa · xH2O
分子量:
494.06 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

检测方案

>98% (HPLC)

颜色

white

溶解性

DMSO: 32 mg/mL
H2O: insoluble

储存温度

2-8°C

SMILES字符串

O.[Na+].CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C([O-])=O)c(SC(C)(C)C)c2c1

InChI

1S/C27H34ClNO2S.Na.H2O/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18;;/h8-14,17H,15-16H2,1-7H3,(H,30,31);;1H2/q;+1;/p-1

InChI key

APMAGPLTTCSTMM-UHFFFAOYSA-M

生化/生理作用

Potent and specific inhibitor of leukotriene biosynthesis.

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Chen-Hsuan Wang et al.
Brain research bulletin, 79(3-4), 169-176 (2009-05-12)
Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Results showed that early induction (at 6h of

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