质量水平
检测方案
≥99%
形式
powder
官能团
ester
脂质类型
neutral glycerides
运输
ambient
储存温度
−20°C
SMILES字符串
CCCCCCCC(=O)OCC(O)CO
InChI
1S/C11H22O4/c1-2-3-4-5-6-7-11(14)15-9-10(13)8-12/h10,12-13H,2-9H2,1H3
InChI key
GHBFNMLVSPCDGN-UHFFFAOYSA-N
应用
- Molecular Simulations and Markov State Modeling of Quorum Sensing Regulators: Research revealed the inactive form of the quorum sensing regulator SdiA in Escherichia coli, offering insights into bacterial communication mechanisms that could be influenced by lipid-based signaling molecules such as 1-Octanoyl-rac-glycerol (Grabski et al., 2021).
生化/生理作用
辛酸甘油酯(1-辛酰-rac-甘油)是一种抗菌单甘酯,可以治疗刚果放线菌和弯曲杆菌感染以及灭活生物表面上 大肠杆菌 、 李斯特菌 和 沙门氏菌 。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 109, 297-315 (2017-08-27)
Development of self-nanoemulsifying drug delivery systems (SNEDDS) of polypeptide-k (PPK) is reported with the aim to achieve its oral delivery. Box-Behnken design (BBD) was adopted to develop and optimize the composition of SNEDDS. Oleoyl polyoxyl-6 glycerides (A), Tween 80 (B)
Journal of pharmaceutical sciences, 106(12), 3613-3622 (2017-09-20)
Present investigation explores the potential of nanostructured lipid carriers (NLCs) for nose to brain delivery of rivastigmine (RV), which is further enhanced by incorporating into an in situ gelling system, increasing retention in nasal cavity. NLCs having particle size of
Journal of microencapsulation, 34(3), 319-333 (2017-05-10)
The objective of this study was to develop and optimise self-nanoemulsifying drug delivery system (SNEDDS) of atorvastatin calcium (ATC) for improving dissolution rate and eventually oral bioavailability. Ternary phase diagrams were constructed on basis of solubility and emulsification studies. The
Oncotarget, 8(55), 94297-94316 (2017-12-08)
In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg), Capmul
Pharmaceuticals (Basel, Switzerland), 13(4) (2020-04-23)
Carvedilol (CRV) is a non-selective blocker of α and β adrenergic receptors, which has been extensively used for the treatment of hypertension and congestive heart failure. Owing to its poor biopharmaceutical properties, CRV has been incorporated into different types of
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