M218
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α4 Subunit) antibody produced in rat
~1 mg/mL, clone mAb 299, purified immunoglobulin, buffered aqueous solution
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Conjugate:
unconjugated
Clone:
mAb 299, monoclonal
Application:
IHC (f), RIA
Citations:
1
biological source
rat
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
mAb 299, monoclonal
form
buffered aqueous solution
species reactivity
human, chicken, rat
concentration
~1 mg/mL
technique(s)
immunohistochemistry (frozen sections): 1:800, radioimmunoassay: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CHRNA4(1137)
rat ... Chrna4(25590)
Immunogen
nicotinic acetylcholine receptor (AchR) from the rat brain.
Biochem/physiol Actions
Binds to native and denatured α4 AchR. May be used to quantitate α4 AchR′s on the cell surface. The epitope is located on the extracellular surface of the α4 subunit of the AchR.
Physical form
Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.
Legal Information
Sold with permission of the Salk Institute
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
V V Pollock et al.
Neuroscience, 158(4), 1311-1325 (2008-12-23)
Neuronal nicotinic receptor alpha4 subunits associated with nicotinic alpha4beta2 receptors are phosphorylated by cyclic AMP-dependent protein kinase (PKA) and protein kinase C (PKC), but the stages of receptor formation during which phosphorylation occurs and the functional consequences of kinase activation
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