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Merck
CN

M218

Sigma-Aldrich

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α4 Subunit) antibody produced in rat

~1 mg/mL, clone mAb 299, purified immunoglobulin, buffered aqueous solution

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MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rat

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

mAb 299, monoclonal

形式

buffered aqueous solution

种属反应性

human, chicken, rat

浓度

~1 mg/mL

技术

immunohistochemistry (frozen sections): 1:800
radioimmunoassay: suitable

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CHRNA4(1137)
rat ... Chrna4(25590)

特异性

Binds to native and denatured α4 AchR. May be used to quantitate α4 AchR′s on the cell surface. The epitope is located on the extracellular surface of the α4 subunit of the AchR.

免疫原

nicotinic acetylcholine receptor (AchR) from the rat brain.

外形

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

法律信息

Sold with permission of the Salk Institute

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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V V Pollock et al.
Neuroscience, 158(4), 1311-1325 (2008-12-23)
Neuronal nicotinic receptor alpha4 subunits associated with nicotinic alpha4beta2 receptors are phosphorylated by cyclic AMP-dependent protein kinase (PKA) and protein kinase C (PKC), but the stages of receptor formation during which phosphorylation occurs and the functional consequences of kinase activation

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