所有图片(1)
别名:
3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride
经验公式（希尔记法）:
C16H24N2O2 · HCl
推荐产品
质量水平
检测方案
≥98% (HPLC)
形式
solid
颜色
off-white
溶解性
H2O: 19 mg/mL
创始人
Endo
SMILES字符串
CCC1=C(C)NC2=C1C(C(CN3CCOCC3)CC2)=O.Cl
InChI
1S/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H
InChI key
GQWNECFJGBQMBO-UHFFFAOYSA-N
基因信息
human ... DRD2(1813) , HTR2A(3356) , MAOA(4128) , MAOB(4129)
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生化/生理作用
D2 dopamine receptor antagonist; MAO inhibitor.
特点和优势
This compound was developed by Endo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
Treatment of morbidly obese psychotic patients with molindone: three case reports.
Robert E McCue et al.
The Journal of clinical psychiatry, 70(11), 1606-1607 (2009-12-25)
M Froimowitz et al.
Drug design and discovery, 15(2), 63-81 (1997-08-01)
This study is an attempt to incorporate the butyrophenones, an important class of nontricyclic antipsychotic drugs, into a previously proposed pharmacophore model of tricyclic dopamine D2 receptor antagonist ligands. Conformational energy calculations were performed using the MM3-92 program on spiperone
R B Rosse et al.
Clinical neuropharmacology, 19(5), 444-450 (1996-10-01)
This preliminary investigation examined the therapeutic efficacy of two doses of oral D-cycloserine (5 and 15 mg p.o. b.i.d.) administered as an adjuvant to molindone (150 mg p.o. q.d.) in the treatment of schizophrenia. D-Cycloserine is an agonist at the
Robert L Findling et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 49(6), 583-594 (2010-05-25)
To examine the long-term safety and efficacy of three antipsychotics in early-onset schizophrenia spectrum disorders. Patients (8 to 19 years old) who had improved during an 8-week, randomized, double-blind acute trial of olanzapine, risperidone, or molindone (plus benztropine) were eligible
Aripiprazole-induced agitation after clozapine discontinuation: a case report.
Dara Y Cho et al.
The Journal of clinical psychiatry, 70(1), 141-143 (2009-02-19)
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