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Merck
CN

M1568

Sigma-Aldrich

甘露糖三氟磺酸酯

For PET imaging, ≥98% (TLC)

别名:

β-D-甘露吡喃糖1,3,4,6-四- O -乙酸盐 2- O -三氟甲磺酸酯, 1,3,4,6-四-O-乙酰基-2-O-三氟甲磺酰-β-D-吡喃甘露糖, TATM, 甘露糖三氟甲磺酸酯

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About This Item

经验公式(希尔记法):
C15H19F3O12S
CAS号:
分子量:
480.36
Beilstein:
4341413
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.12

质量水平

方案

≥98% (TLC)

表单

powder

技术

PET imaging: suitable

运输

dry ice

储存温度

−20°C

SMILES字符串

CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChI

1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1

InChI key

OIBDVHSTOUGZTJ-PEBLQZBPSA-N

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一般描述

Mannose triflate is a glucose analogue.

应用

Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. The binding of 18F to the mannose triflate has been carried out via SN2 nucleophilic substitution reaction. It is used in computational tomography, an imaging technique in early detection of cancer.

其他说明

This formulation of mannose triflate has reduced trace impurities that are known to cause lower synthetic yields.

应用

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ren Iwata et al.
Journal of labelled compounds & radiopharmaceuticals, 61(7), 540-549 (2018-03-10)
High specific activity is often a significant requirement for radiopharmaceuticals. To achieve that with fluorine-18 (18 F)-labeled probes, it is mandatory to start from no-carrier-added fluoride and to reduce to a minimum the amount of precursor in order to decrease
Padgett, H., et al.
Applied Radiation and Isotopes, 40, 433-433 (1989)
Shane B Claggett et al.
EJNMMI research, 3(1), 53-53 (2013-07-17)
Many automated radiosynthesizers for producing positron emission tomography (PET) probes provide a means for the operator to create custom synthesis programs. The programming interfaces are typically designed with the engineer rather than the radiochemist in mind, requiring lengthy programs to
Salvador Castaneda Vega et al.
NeuroImage, 155, 245-256 (2017-05-06)
The clinical use of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) has proven to be a strong diagnostic tool in the field of neurology. The reliability of these methods to confirm clinical diagnoses has guided preclinical research to
Martin Thunemann et al.
Nature communications, 8(1), 444-444 (2017-09-07)
Many pathophysiological processes are associated with proliferation, migration or death of distinct cell populations. Monitoring specific cell types and their progeny in a non-invasive, longitudinal and quantitative manner is still challenging. Here we show a novel cell-tracking system that combines

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