推荐产品
产品线
BioXtra
质量水平
杂质
≤0.2% Total Impurities
灼烧残渣
≤0.1%
颜色
white to light yellow
mp
159-161 °C (lit.)
溶解性
acetic acid: 0.1 M, clear, colorless to yellow
痕量阴离子
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
痕量阳离子
Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Na: ≤0.01%
Pb: ≤0.001%
Zn: ≤0.0005%
抗生素抗菌谱
Gram-negative bacteria
parasites
作用机制
DNA synthesis | interferes
储存温度
2-8°C
SMILES字符串
CC1=NC=C([N+]([O-])=O)N1CCO
InChI
1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
InChI key
VAOCPAMSLUNLGC-UHFFFAOYSA-N
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相关类别
一般描述
化学结构:咪唑
应用
甲硝唑用于研究DNA损伤和修复,并可诱导猪痢疾密螺旋体(Brachyspira hyodysenteriae)中的基因转移因子VSH-1。 它通常用于治疗牙周炎,并用于生物利用度研究。
生化/生理作用
甲硝哒唑是一种前药,对厌氧菌具有选择性,因为它们能够在细胞内将甲硝哒唑还原为活性形式。还原甲硝唑与脱氧核糖核酸共价结合,破坏其螺旋结构,诱导脱氧核糖核酸链断裂并抑制细菌核酸合成。最终导致细菌细胞死亡。
相关产品
产品编号
说明
价格
警示用语:
Danger
危险声明
危险分类
Carc. 1B - Muta. 1B - STOT RE 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Tal Frolinger et al.
Scientific reports, 9(1), 3546-3546 (2019-03-07)
Dietary polyphenols promote memory in models of sleep deprivation (SD), stress, and neurodegeneration. The biological properties of dietary polyphenols greatly depend upon the bioavailability of their phenolic metabolites derivatives, which are modulated by gut microbiota. We recently demonstrated that supplementation
Fabrizio Palumbo et al.
Cell reports, 32(8), 108054-108054 (2020-08-28)
Operant learning requires multiple cognitive processes, such as learning, prediction of potential outcomes, and decision-making. It is less clear how interactions of these processes lead to the behavioral adaptations that allow animals to cope with a changing environment. We show
Christina M Surawicz et al.
The American journal of gastroenterology, 108(4), 478-498 (2013-02-27)
Clostridium difficile infection (CDI) is a leading cause of hospital-associated gastrointestinal illness and places a high burden on our health-care system. Patients with CDI typically have extended lengths-of-stay in hospitals, and CDI is a frequent cause of large hospital outbreaks
T H I Brummer et al.
BJOG : an international journal of obstetrics and gynaecology, 120(10), 1269-1276 (2013-06-22)
To evaluate cefuroxime and metronidazole antibiotic prophylaxis. Observational nonrandomised 1-year prospective cohort study. Fifty-three hospitals in Finland. A total of 5279 women undergoing hysterectomy for benign indications, with cefuroxime given to 4301 and metronidazole given to 2855. Excluding other antibiotics
Dina Zandbergen et al.
Journal of periodontology, 84(3), 332-351 (2012-05-23)
The treatment of periodontitis frequently begins with a non-surgical phase that includes scaling and root planing (SRP) and, on occasion, the use of systemic antibiotics. The goal of this review is to systematically evaluate the data concerning the effect of
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