产品名称
IgM, Kappa 来源于鼠骨髓瘤, clone TEPC 183, ascites fluid, lyophilized powder
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
clone
TEPC 183, monoclonal
form
lyophilized powder
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
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相关类别
Application
IgM, Kappa from murine myeloma has been used as a control to study its effects on brain derived synaptic plasticity.
Biochem/physiol Actions
IgM antibodies are present as pentamers in serum and are produced in response to antigens.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
The TEPC-183 tumor line that produces mouse IgM is a tetramethylpentadecane (pristane) induced plasmacytoma, originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.
Preparation Note
Reconstitute with 1 ml deionized water.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
D M Reinitz et al.
Infection and immunity, 58(7), 2337-2342 (1990-07-01)
The T-cell dependency of B-cell responses to variant surface glycoprotein (VSG) epitopes exposed in their native surface conformation on Trypanosoma brucei rhodesiense clone LouTat 1 was investigated. T-cell requirements were examined by analyses of gamma globulin preparations derived from trypanosome-infected
Brian O'Nuallain et al.
Journal of neurochemistry, 119(1), 189-201 (2011-07-26)
Diverse lines of evidence indicate that pre-fibrillar, diffusible assemblies of the amyloid β-protein (Aβ) play an important role in Alzheimer's disease pathogenesis. Although the precise molecular identity of these soluble toxins remains unsettled, recent experiments suggest that sodium dodecyl sulfate
The Immunoglobulins: Structure and Function (1998)
A monoclonal antibody against synthetic A beta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting A beta
ONuallain B, et al.
Journal of Neurochemistry, 119(1), 189-201 (2011)
Molecular Genetics of Immunoglobulin, 17 (1987)
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