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质量水平
方案
≥98% (TLC)
表单
powder
mp
149-150 °C (lit.)
溶解性
chloroform: 100 mg/mL, clear, colorless
荧光
λex 312 nm in methanol
λex 360 nm; λem 499 nm (Reaction product)
储存温度
−20°C
SMILES字符串
CC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1
InChI
1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3
InChI key
HXVZGASCDAGAPS-UHFFFAOYSA-N
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警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Latent blue and red fluorophores based on the trimethyl lock.
Luke D Lavis et al.
Chembiochem : a European journal of chemical biology, 7(8), 1151-1154 (2006-06-07)
Abha Kathuria et al.
Bioorganic & medicinal chemistry, 17(4), 1550-1556 (2009-02-03)
Calreticulin Transacetylase (CRTAase) catalyzes the transfer of acetyl groups from polyphenolic acetates (PAs) to the receptor proteins and modulates their biological activities. CRTAase was conveniently assayed by the irreversible inhibition of cytosolic glutathione S-transferase (GST) by the model acetoxycoumarin, 7,8-diacetoxy-4-methylcoumarin
M L Graber et al.
The American journal of physiology, 250(1 Pt 2), F159-F168 (1986-01-01)
Intracellular pH (pHi) of turtle bladder mucosal cells was studied by the trapped fluorescent indicator technique. Bladders efficiently accumulated and converted 4-methylumbelliferyl acetate to its pH-sensitive derivative 4-methylumbelliferone (4MU). Excited at the pH-indifferent wavelength 334 nm, bladders fluoresced a uniform
H A Berman et al.
Biochemistry, 29(47), 10640-10649 (1990-11-27)
This paper examines covalent reactivity of AchE with respect to cationic and uncharged methylphosphonates and substrates in the absence and presence of cationic ligands selective for the active center and the peripheral anionic site. The organophosphorus inhibitors are enantiomeric alkyl
H G Raj et al.
Bioorganic & medicinal chemistry, 9(5), 1085-1089 (2001-05-30)
Our earlier work established a convenient assay procedure for acetoxycoumarin (AC): protein transacetylase (TA) by indirectly quantifying the activity of glutathione (GSH)-S-transferase (GST), the extent of inhibition of GST under the conditions of the assay represented TA activity. In this
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