所有图片(1)
About This Item
经验公式（希尔记法）:
C46H64N5O8PS
CAS号:
分子量:
878.07
MDL编号:
UNSPSC代码:
41116105
PubChem化学物质编号:
NACRES:
NA.21
产品线
Proligo Reagents
质量水平
检测方案
≥96% (31P-NMR)
适用性
conforms to structure for H-NMR
相容性
configured for ABI
储存温度
−20°C
SMILES字符串
COc1ccc(cc1)C(N2C3CS[C@@H](CCCCC(=O)NCCOCCOCCOP(OCCC#N)N(C(C)C)C(C)C)C3NC2=O)(c4ccccc4)c5ccc(OC)cc5
InChI
1S/C46H64N5O8PS/c1-34(2)51(35(3)4)60(58-27-12-25-47)59-32-31-57-30-29-56-28-26-48-43(52)16-11-10-15-42-44-41(33-61-42)50(45(53)49-44)46(36-13-8-7-9-14-36,37-17-21-39(54-5)22-18-37)38-19-23-40(55-6)24-20-38/h7-9,13-14,17-24,34-35,41-42,44H,10-12,15-16,26-33H2,1-6H3,(H,48,52)(H,49,53)/t41-,42-,44-,60?/m0/s1
InChI key
WSDQYLGSIUJJRU-ZMKGMYJVSA-N
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一般描述
Biotin phosphoramidite is a reagent used to directly incorporate a biotin label at the 5′ hydroxy group of the terminal nucleoside base through a p-aminophenethyl spacer group during oligonucleotide synthesis. Biotin-labelled oligonucleotides have become extremely popular in DNAcapture and detection applications, due to their very high-sensitivity and strong, specific binding affinity with avidin and streptavidin proteins. Biotinbased detection methods and are widely used by researchers. Biotin labelling is compatible with PCR and most hybridization techniques.
Key Features of Biotin Phosphoramidite
Key Features of Biotin Phosphoramidite
- Behaves like any standard phosphoramidite on the DNA synthesizer
- Readily soluble in acetonitrile
- Biotin compound has a dimethoxytrityl (DMT) group on the ring structure,which allows coupling-yield determination and trityl-selective purification
- A long, water-compatible linker arm ensures maximum sensitivity
- Provides a coupling efficiency of at least 95%The product is configured for ABI™ Synthesizers
法律信息
ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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