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Merck
CN

M0418

Sigma-Aldrich

黑色素

BioReagent, Synthetic, suitable for cell culture

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About This Item

CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.75

生物来源

synthetic

产品线

BioReagent

检测方案

≥97% (TLC)

形式

powder

技术

cell culture | mammalian: suitable

溶解性

1 N NH4OH: 20 mg/mL

储存温度

−20°C

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

InChI key

XUMBMVFBXHLACL-UHFFFAOYSA-N

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一般描述

黑色素是一种独特的色素,存在于动物、植物、细菌和真菌中。它是由酚类化合物和吲哚类化合物聚合而成的无定形聚合物。

应用

黑色素已用于:
  • 培养正常人角质形成细胞进行Masson-Fontana染色
  • 作为测定正常人表皮黑色素细胞和永生人角质形成细胞中黑色素含量的标准品
  • 作为模拟人体皮肤或黑素细胞痣和黑素瘤的吸收剂

生化/生理作用

黑色素在伪装和能量采集中起着重要作用。它还有助于防止电离紫外线辐射,生物因子防护,如宿主对病原体的防御,以及非生物因素防护,如热,冷和渗透胁迫。黑色素作为一种有效的阳离子螯合剂,因为有利于自由基清除活动,所以是一些光保护霜的组分。黑色素可用作细胞培养物的光保护剂。

制备说明

通过使用过氧化氢对酪氨酸进行氧化制备。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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