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Merck
CN

M006

丙谷胺 钠盐

solid

别名:

4-苯甲酰氨基-5-二丙氨基-5-氧代戊酸 钠-钾盐, N-苯甲酰基-N′,N′-二丙基-DL-异谷氨酰胺 钠-钾盐

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关于此项目

经验公式(希尔记法):
C18H25N2NaO4
化学文摘社编号:
分子量:
356.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
solid
Quality level:
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form

solid

Quality Level

color

white

solubility

H2O: soluble

SMILES string

[Na+].CCCN(CCC)C(=O)C(CCC([O-])=O)NC(=O)c1ccccc1

InChI

1S/C18H26N2O4.Na/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14;/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22);/q;+1/p-1

InChI key

UFMWGCINVOIJSO-UHFFFAOYSA-M

Gene Information

human ... CCK(885), CCKAR(886), CCKBR(887)
mouse ... CCK(12424)
rat ... CCK(25298)

Application

丙谷胺钠盐已被用于研究丙谷胺对欧洲鲈鱼,舌齿鲈中宏营养物质选择的影响。

Biochem/physiol Actions

丙谷胺钠盐是一种非肽胆囊收缩素受体拮抗剂,其对CCKA亚型具有更高的选择性。它可有选择地阻止中枢神经系统的影响。丙谷胺钠盐具有口服活性。
CCK拮抗剂;选择性地阻断CNS效应。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E S Corp et al.
Physiology & behavior, 61(6), 823-827 (1997-06-01)
Cholecystokinin (CCK) receptors are classified as two subtypes, designated CCK(A) and CCK(B), and both subtypes are found in brain and peripheral tissues of rats. CCK-8 has been shown to act peripherally to reduce meal size, and this satiating action can
Role of cholecystokinin and its antagonist proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.
V. C. Rubio
Physiology & Behavior (2008)
The cholecystokinin antagonist, proglumide, increases food intake in the rat
G.Shillabeer and J. Davidson
Regulatory Peptides (1984)



全球贸易项目编号

货号GTIN
M006-500MG04061832677194
M006-100MG04061833992500