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生物来源
microbial
质量水平
检测方案
≥90% (HPLC)
形式
powder
溶解性
water: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
Cl.CC(C)CC(NC(C)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C=O
InChI
1S/C20H38N6O4.ClH/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);1H
InChI key
OQQYPQNFLLAILR-UHFFFAOYSA-N
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生化/生理作用
丝氨酸和半胱氨酸蛋白酶抑制剂。抑制纤溶酶、胰蛋白酶、木瓜蛋白酶、钙蛋白酶和组织蛋白酶 B。不抑制胃蛋白酶、组织蛋白酶 A 和 D、凝血酶或 α-糜蛋白酶。有效浓度 10-100 μM。已有许多研究使用亮肽素预防由声过度刺激或耳毒性抗生素庆大霉素引起的听力丧失。（耳蜗毛细胞的丢失被认为是由钙蛋白酶介导的。）
分析说明
亮肽素在溶液中形成互变异构体，因此HPLC分析时会出现多个峰。大多数污染性肽是外消旋化的亮肽素。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
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