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形式
buffered aqueous solution
比活
≥250 units/mg protein (Lowry)
UniProt登记号
运输
wet ice
储存温度
2-8°C
基因信息
human ... PNLIP(5406)
一般描述
Pancreatic lipase fulfills a key function in dietary fat absorption by hydrolyzing triglycerides into diglycerides and subsequently into monoglycerides and free fatty acids.
应用
Lipase has been used in a study to assess the effects of acidification on human milk′s cellular and nutritional content. It has also been used in a study to investigate the effect of physical training on the adipose tissue of diet-induced obesity mice.
生化/生理作用
可水解甘油三酯、甘油二酯、甘油单酯（速率依次递减）。
The hormone leptin reduces pancreatic secretion and expression of lipase and has been shown to directly inhibit its activity.
单位定义
One unit will liberate 1.0 μmole of 2-monoglyceride from 1,2-diglyceride per min at pH 8.1 at 37 °C.
外形
Solution in 0.1 M Tris containing 0.1 M NaCl and serine protease inhibitor
分析说明
通过 Lowry 法确定的蛋白质。
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Nili Elinson et al.
The British journal of nutrition, 96(4), 691-696 (2006-10-03)
Leptin, a metabolic regulator of energy expenditure, exerts its peripheral effects primarily by altering lipid metabolism. The exocrine pancreas has a key role in the digestion of dietary lipids, but the role of leptin in regulating pancreatic lipases remains unknown.
The effects of acidification on human milk's cellular and nutritional content
Erickson, T., et al.
Journal of Perinatology : Official Journal of the California Perinatal Association, doi: 10-doi: 10 (2012)
J M de Farias et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 45(3), 190-196 (2012-09-14)
It is well known that high-fat diets (HFDs) induce obesity and result in an increase in oxidative stress in adipose tissue, which leads to an impairment of fat mobilization by a downregulation of the lipases, such as hormone-sensitive lipase (HSL)
J Hall et al.
The Journal of small animal practice, 54(5), 275-279 (2013-02-13)
Mushroom toxicosis is rarely diagnosed in dogs and is poorly reported in the veterinary literature. This report suggests that mushroom toxicosis is a potentially under-diagnosed condition in first opinion practice in the UK. Nine dogs with clinical signs consistent with
Minshan Hu et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 21(6), 751-757 (2013-03-05)
Diet induces changes in plasma lipid profiles, and the plasma lipid profiles vary among different genetic backgrounds. The aim of this study was to investigate how a high-carbohydrate (high-CHO) diet interacts with hepatic lipase G-250A promoter polymorphism to affect the
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