产品线
BioReagent
形式
lyophilized powder
包装
vial of 50 μg
适用性
suitable for protein sequencing
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
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一般描述
亮氨酸氨肽酶 (LAP) 是一种蛋白水解酶。它是一种氨基酸水解酶，催化蛋白质或肽氨基末端亮氨酸残基的水解。LAP 在肝脏、肾脏、肺和血清中天然存在。
应用
亮氨酸氨基肽酶可用于：
- 蛋白质组学分析
- 用作蛋白质解聚反应的预处理剂
- 测试其对人重组IL-8降解的影响
生化/生理作用
在肝损伤、肝硬化、肝炎和其他疾病状态下下，血清亮氨酸氨基肽酶(LAP )活性会增加，因此 LAP 可用作药物引起的肝损伤生物标志物。LAP表达异常会导致肿瘤细胞增殖、血管生成和侵袭，因此也可用作癌症相关的生物标志物。
单位定义
一个单位在37°C 下 pH 7.2 时每分钟将水解 1.0μ摩尔 L-亮氨酸-对硝基苯胺为 L -亮氨酸和对硝基苯胺（25°C 下可获得活性约为37°C 下的 40%）。以 L-亮氨酸对硝基苯胺为底物得到的活性是以 L-亮氨酸酰胺为底物得到的活性的 2-5 倍。
警示用语：
Danger
危险分类
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
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