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安全信息

L9773

Sigma-Aldrich

Luteinizing Hormone from equine pituitary

pkg of ~15 units/vial

别名:

ICSH, LH, PLH

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About This Item

CAS号:
EC 号:
MDL编号:
UNSPSC代码:
51111800

形式

powder

质量水平

包装

pkg of ~15 units/vial

溶解性

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

UniProt登记号

运输

ambient

储存温度

2-8°C

基因信息

应用

Luteinizing hormone (LH) has been used to study effect of LH on the development of preantral follicles for nuclear maturation of ovine oocytes and as an endocrine signal to study circadian phase in the ovary.

生化/生理作用

Two chain glycoprotein hormone, the α-chain is not active, biological specificity is attributed to the β-chain; induces ovulation, spermatogenesis, and synthesis of sex steroids.

包装

Package size based on NIH standard LH-S1 using the rat Leydig cell assay

数量

One NIH LH-S1 unit = approx. 2,000 I.U.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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Timing of the Ovarian Circadian Clock Is Regulated by Gonadotropins
Tomoko Y
Endocrinology (2009)
Nuclear maturation of ovine oocytes in cultured preantral follicles
G Tamilmani
The Journal of Small Animal Practice (2005)
Tomoko Yoshikawa et al.
Endocrinology, 150(9), 4338-4347 (2009-06-13)
The timing of ovulation is critically important to the success of reproduction. Current thinking attributes the timing of ovulation to LH secretion by the pituitary, itself timed by signals from the hypothalamus. The discovery of an internal circadian timer in
Hidetoshi Hasuwa et al.
Science (New York, N.Y.), 341(6141), 71-73 (2013-06-15)
Ovulation in the mouse and other mammals is controlled by hormones secreted by the hypothalamo-pituitary-ovarian axis. We describe anovulation and infertility in female mice lacking the microRNAs miR-200b and miR-429. Both miRNAs are strongly expressed in the pituitary gland, where
Rachel Y Cheong et al.
Endocrinology, 155(4), 1418-1427 (2014-01-31)
The negative feedback mechanism through which 17β-estradiol (E2) acts to suppress the activity of the GnRH neurons remains unclear. Using inducible and cell-specific genetic mouse models, we examined the estrogen receptor (ER) isoforms expressed by neurons that mediate acute estrogen

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