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一般描述
研究领域：细胞结构
Lipodisq®聚合物包含苯乙烯和马来酸单体单元。本品是SMA聚合物的预水解形式（pre-hydrolyzed form），具有苯乙烯和马来酸单体。这类聚合物-脂质复合物主要通过无洗涤剂的方法制备。
有效pH范围：6.0 - 9.0
Lipodisq®聚合物包含苯乙烯和马来酸单体单元。本品是SMA聚合物的预水解形式（pre-hydrolyzed form），具有苯乙烯和马来酸单体。这类聚合物-脂质复合物主要通过无洗涤剂的方法制备。
有效pH范围：6.0 - 9.0
应用
Lipodisq®试剂是来源于苯乙烯和马来酸的新型聚合物。 Lipodisq聚合物能够形成可在膜蛋白中结合的纳米脂质盘状颗粒。Lipodisq技术可以在不使用表面活性剂的情况下溶解常用的脂质，例如二肉豆蔻酰磷脂酰胆碱（DMPC）。通常，lipodisq聚合物有望用于减少膜蛋白增溶用洗涤剂的使用。在pH 7.4下，Lipodisqs的直径通常为9-10 纳米。
法律信息
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
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产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Indra D Sahu et al.
Biochemistry, 52(38), 6627-6632 (2013-08-30)
Pulsed EPR DEER structural studies of membrane proteins in a lipid bilayer have often been hindered by difficulties in extracting accurate distances when compared to those of globular proteins. In this study, we employed a combination of three recently developed
Juan F Bada Juarez et al.
Chemistry and physics of lipids, 222, 51-58 (2019-05-19)
Lipodisq™ nanoparticles have been used to extract surface lipids from the cuticle of two strains (wild type, N2 and the bacteria-resistant strain, agmo-1) of the C. elegans nematode without loss of viability. The extracted lipids were characterized by thin layer
Detergent-Free Formation and Physicochemical Characterization of Nanosized Lipid-Polymer Complexes: Lipodisq
Orwick MC, et al.
Angewandte Chemie (International ed. in English), 51(19), 4653-4657 (2012)
Maria Lyngaas Torgersen et al.
Journal of biomedical nanotechnology, 16(4), 419-431 (2020-09-25)
Many promising pharmaceutically active compounds have low solubility in aqueous environments and their encapsulation into efficient drug delivery vehicles is crucial to increase their bioavailability. Lipodisq nanoparticles are approximately 10 nm in diameter and consist of a circular phospholipid bilayer
Masafumi Tanaka et al.
Chemistry and physics of lipids, 232, 104954-104954 (2020-08-23)
Lipid emulsions are potential carriers for poorly water-soluble drugs. Previously, we revealed that lipid nanoparticles complexed with styrene maleic acid copolymer (SMA) disintegrate under acidic pH. In the present study, SMA-containing lipid emulsions (SMA emulsions) were prepared and their physicochemical
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