L9125
L -亮氨酸- p -硝基苯胺
leucine aminopeptidase substrate, chromogenic, ≥98% (TLC), powder
别名:
L-亮氨酸-4-硝基苯胺
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关于此项目
经验公式（希尔记法）:
C12H17N3O3
化学文摘社编号:
分子量:
251.28
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
224-047-3
MDL number:
Beilstein/REAXYS Number:
2218433
产品名称
L -亮氨酸- p -硝基苯胺, leucine aminopeptidase substrate
InChI
1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1
SMILES string
CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI key
AXZJHDNQDSVIDR-NSHDSACASA-N
assay
≥98% (TLC)
form
powder
solubility
ethanol: 50 mg/mL
storage temp.
2-8°C
Quality Level
General description
用于比色法测定亮氨酸氨肽酶的底物。
Application
L-亮氨酸-p-硝基苯胺用为底物，可用于：
- 测定虹鳟幼鱼肠道亮氨酸氨基肽酶的活性（虹鳟）
- 胰岛素调节氨肽酶的抑制分析
- 测定外肽酶的活性
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Natasa Bozić et al.
Electrophoresis, 26(12), 2476-2480 (2005-05-28)
A general method for detecting leucyl aminopeptidase activity after native polyacrylamide gel electrophoresis (PAGE) in situ is described. The method is based on diazotization of p-nitroaniline, liberated in the polyacrylamide gel by leucyl aminopeptidase action on leucine-p-nitroanilide (LpNA) and subsequent
Antioxidant response and body composition of whiteleg shrimp co-cultured with Nile tilapia in recirculating aquaculture
Sharawy ZZ, et al.
Aquaculture Environment Interactions, 9(3), 257-268 (2017)
Reishi Toshiyama et al.
Oncogene, 38(2), 244-260 (2018-08-10)
Previous studies highlighted that aminopeptidase N (APN)/CD13 acts as a scavenger in the survival of hepatocellular carcinoma (HCC) stem cells by reducing reactive oxygen species (ROS) levels. Hence, it has been proposed that APN/CD13 inhibition can increase cellular ROS levels
C Toma et al.
Infection and immunity, 64(11), 4495-4500 (1996-11-01)
The structural gene for the Vibrio cholerae leucine aminopeptidase (lap) was cloned and sequenced. The cloned DNA fragment contained a 1,503-bp open reading frame potentially encoding a 501-amino-acid polypeptide with a calculated molecular mass of 54,442 Da. The deduced amino
Pablo Emiliano Cantón et al.
Frontiers in physiology, 10, 1553-1553 (2020-01-24)
Nezara viridula is a polyphagous stink bug that feeds on crops of economic importance such as corn, soybean and cotton. To increase understanding of the ability of this pest insect to feed on such diverse cropping systems, we analyzed the
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