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Merck
CN

L9125

Sigma-Aldrich

L -亮氨酸- p -硝基苯胺

leucine aminopeptidase substrate, chromogenic, ≥98% (TLC), powder

别名:

L-亮氨酸-4-硝基苯胺

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About This Item

经验公式(希尔记法):
C12H17N3O3
CAS号:
分子量:
251.28
Beilstein:
2218433
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32

产品名称

L -亮氨酸- p -硝基苯胺, leucine aminopeptidase substrate

质量水平

方案

≥98% (TLC)

表单

powder

溶解性

ethanol: 50 mg/mL

储存温度

2-8°C

SMILES字符串

CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1

InChI key

AXZJHDNQDSVIDR-NSHDSACASA-N

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应用

L-亮氨酸-p-硝基苯胺用为底物,可用于:
  • 测定虹鳟幼鱼肠道亮氨酸氨基肽酶的活性(虹鳟
  • 胰岛素调节氨肽酶的抑制分析
  • 测定外肽酶的活性

底物

用于比色法测定亮氨酸氨肽酶的底物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C Toma et al.
Infection and immunity, 64(11), 4495-4500 (1996-11-01)
The structural gene for the Vibrio cholerae leucine aminopeptidase (lap) was cloned and sequenced. The cloned DNA fragment contained a 1,503-bp open reading frame potentially encoding a 501-amino-acid polypeptide with a calculated molecular mass of 54,442 Da. The deduced amino
Antioxidant response and body composition of whiteleg shrimp co-cultured with Nile tilapia in recirculating aquaculture
Sharawy ZZ, et al.
Aquaculture Environment Interactions, 9(3), 257-268 (2017)
Pablo Emiliano Cantón et al.
Frontiers in physiology, 10, 1553-1553 (2020-01-24)
Nezara viridula is a polyphagous stink bug that feeds on crops of economic importance such as corn, soybean and cotton. To increase understanding of the ability of this pest insect to feed on such diverse cropping systems, we analyzed the
Natasa Bozić et al.
Electrophoresis, 26(12), 2476-2480 (2005-05-28)
A general method for detecting leucyl aminopeptidase activity after native polyacrylamide gel electrophoresis (PAGE) in situ is described. The method is based on diazotization of p-nitroaniline, liberated in the polyacrylamide gel by leucyl aminopeptidase action on leucine-p-nitroanilide (LpNA) and subsequent
Reishi Toshiyama et al.
Oncogene, 38(2), 244-260 (2018-08-10)
Previous studies highlighted that aminopeptidase N (APN)/CD13 acts as a scavenger in the survival of hepatocellular carcinoma (HCC) stem cells by reducing reactive oxygen species (ROS) levels. Hence, it has been proposed that APN/CD13 inhibition can increase cellular ROS levels

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