推荐产品
应用
Lipodisq®与棕榈酰油酰磷脂酰胆碱（POPC）和棕榈酰油酰磷脂酰甘油（POPG）一起可用于纳米颗粒制备。
Lipodisq®试剂是来源于苯乙烯和马来酸的新型聚合物。 Lipodisq聚合物能够形成可在膜蛋白中结合的纳米脂质盘状颗粒。Lipodisq技术可以在不使用表面活性剂的情况下溶解常用的脂质，例如二肉豆蔻酰磷脂酰胆碱（DMPC）。通常，lipodisq聚合物有望用于减少膜蛋白增溶用洗涤剂的使用。在pH 7.4下，Lipodisqs的直径通常为9-10 纳米。
生化/生理作用
Lipodisq®不含洗涤剂，可用于膜蛋白生物物理研究，包括电子显微镜（EM）、圆二色性（CD）、电子顺磁共振（EPR）和核磁共振（NMR）技术以及递送载体。
法律信息
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Characterization and Chemical Modification of the Silica Surface, 415-415 (2019)
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Orwick MC, et al.
Angewandte Chemie (International ed. in English), 51(19), 4653-4657 (2012)
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Chemistry and physics of lipids, 221, 167-175 (2019-04-04)
Nanoparticles assembled with poly(styrene-maleic acid) copolymers, identified in the literature as Lipodisq, SMALPs or Native Nanodisc, are routinely used as membrane mimetics to stabilise protein structures in their native conformation. To date, transmembrane proteins of varying complexity (up to 8
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