生物来源
bacterial (Erwinia herbicola)
质量水平
检测方案
≥98% (TLC)
形式
powder
技术
thin layer chromatography (TLC): suitable
颜色
white
溶解性
water: 9.80-10.20 mg/mL, cloudy to hazy, colorless to faintly yellow
储存温度
2-8°C
InChI
1S/C18H32O16/c19-1-7-10(23)14(27)17(5-21,33-7)31-3-9-12(25)15(28)18(6-22,34-9)30-2-8-11(24)13(26)16(29,4-20)32-8/h7-15,19-29H,1-6H2/t7-,8-,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-/m1/s1
InChI key
ZFTFOHBYVDOAMH-XNOIKFDKSA-N
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一般描述
Levan果聚糖是产自某些微生物和植物的多糖。它是果糖分子以β-(2→6)形式连接而成的非典型生物聚合物。Levan果聚糖是一种胞外多糖（细胞外合成）。
应用
Levan果聚糖（来源于草生欧文氏菌Erwinia herbicola）已用于：
- 作为核磁共振波谱法(NMR)的标准品，分析甜菜糖蜜培养基中地衣芽孢杆菌Bacillus licheniformis NS032生产的levan果聚糖
- 作为多糖底物，检测科普里普氏菌Prevotella copri菌株以多糖为唯一碳源的体外生长能力
- 作为果聚糖酶活性检测底物
生化/生理作用
Levan果聚糖可用于化妆品、药品或纳米技术等多种工业应用。具有抗高血糖和抗肿瘤作用，可防止糖尿病诱导的氧化应激，可提高心脏中的过氧化氢酶(CAT)和超氧化物歧化酶(SOD)水平。Levan果聚糖还具有免疫调节和益生作用。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Susanne L Jensen et al.
International journal of biological macromolecules, 85, 514-521 (2016-01-17)
A Levanase, LevB, from Bacillus subtilis 168, was expressed as a His6-tagged protein in Escherichia coli. The enzyme was purified and characterised for its activity and substrate specificity. LevB has a pH optimum of 6.0-6.5 and a maximum observed specific
Hannah Fehlner-Peach et al.
Cell host & microbe, 26(5), 680-690 (2019-11-15)
Gut-dwelling Prevotella copri (P. copri), the most prevalent Prevotella species in the human gut, have been associated with diet and disease. However, our understanding of their diversity and function remains rudimentary because studies have been limited to 16S and metagenomic surveys
An evaluation of the prebiotic potential of microbial levans from Erwinia sp. 10119
Liu C, et al.
Journal of functional foods, 64, 103668-103668 (2020)
Payal Joglekar et al.
mSphere, 3(3) (2018-05-26)
Genomic differences between gut-resident bacterial strains likely underlie significant interindividual variation in microbiome function. Traditional methods of determining community composition, such as 16S rRNA gene amplicon sequencing, fail to capture this functional diversity. Metagenomic approaches are a significant step forward
G D Gojgic-Cvijovic et al.
International journal of biological macromolecules, 121, 142-151 (2018-10-07)
The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100-140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L
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