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Merck
CN
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安全信息

L8638

Sigma-Aldrich

Long chain alkylamine controlled pore glass

120-200 mesh, nominal diameter 500 Å

别名:

LCAA-CPG

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About This Item

MDL编号:
UNSPSC代码:
12352200

粒径

120-200 mesh

孔径

500 Å nominal diameter

应用

Long chain alkylamine controlled pore glass is used in chromatography. Long chain alkylamine controlled pore glass has been used to develop a novel method for the immobilization of nucleotides and for the synthesis of DNA oligonucleotides and their 3′- or (3′,5′)-conjugates.

其他说明

Ligand is mixture of primary and secondary alkylamines, approx. 1:1.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

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Release of DNA oligonucleotides and their conjugates from controlled-pore glass under thermolytic conditions
Grajkowski, A., et al.
Current Protocols in Nucleic Acid Chemistry / Edited By Serge L. Beaucage ... [Et Al.], 3-3 (2008)
Caren L Freel Meyers et al.
Organic letters, 5(3), 341-344 (2003-01-31)
[reaction: see text] A novel method for the immobilization of nucleotides has been developed. The strategy employs a highly reactive pyrrolidinium phosphoramidate zwitterion intermediate that undergoes nucleophilic attack by long-chain alkylamine-controlled pore glass (LCAA-CPG) to generate an immobilized nucleotide. Quantification
Andrzej Grajkowski et al.
Bioconjugate chemistry, 19(8), 1696-1706 (2008-07-24)
The functionalization of long chain alkylamine controlled-pore glass (CPG) with a 3-hydroxypropyl-(2-cyanoethyl)thiophosphoryl linker and its conversion to the support 7 has led to the synthesis of DNA oligonucleotides and their 3'- or (3',5')-conjugates. Indeed, CPG support 7 has been successfully

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