一般描述
凝集素是一种碳水化合物结合蛋白，存在于植物的根、根茎、叶、种子和茎中。凝集素不仅存在于细胞核中，也存在于细胞质中。
应用
来自紫藤的凝集素已用于：
- 通过免疫荧光法研究小鼠脑外神经网和小白蛋白网
- 通过微孔板法评估N-乙酰半乳糖胺（GalNAc）转移到高斯荧光素酶（GLuc）底物的量
- 研究对周围神经网的结合作用
生化/生理作用
凝集素与多糖、糖脂和糖蛋白的聚糖具有高亲和力。它参与植物的防御反应。
WFA不是血型特异性的，但对N-乙酰基-D- 半乳糖胺具有亲和力。
包装
包装尺寸基于蛋白质含量
分析说明
凝集活性以 μg/ml表示，并且是基于1mg/ml磷酸盐缓冲盐水（pH 6.8）的系列稀释液进行测定的。该活性是在25℃条件下温育1小时后凝集2％人血型A红细胞悬浮液的最低浓度。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
Nausicaä Lannoo et al.
Frontiers in plant science, 5, 397-397 (2014-08-29)
Plants are under constant attack from pathogens and herbivorous insects. To protect and defend themselves, plants evolved a multi-layered surveillance system, known as the innate immune system. Plants sense their encounters upon perception of conserved microbial structures and damage-associated patterns
Markus Morawski et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 369(1654), 20140046-20140046 (2014-09-17)
Perineuronal nets (PNs) in the brains of tenascin-R-deficient (tn-r(-/-)) mice develop in temporal concordance with those of wild-type (tn-r(+/+)) mice. However, the histological appearance of PNs is abnormal in adult tn-r(-/-) mice. Here, we investigated whether similar defects are also
Lectins, lectin genes, and their role in plant defense.
M J Chrispeels et al.
The Plant cell, 3(1), 1-9 (1991-01-01)
Dorothy Fiete et al.
The Journal of biological chemistry, 287(34), 29194-29203 (2012-06-23)
Two closely related β1,4-N-acetylgalactosaminyltransferases, β4GalNAc-T3 and β4GalNAc-T4, are thought to account for the protein-specific addition of β1,4-linked GalNAc to Asn-linked oligosaccharides on a number of glycoproteins including the glycoprotein hormone luteinizing hormone and carbonic anhydrase-6 (CA6). We have utilized soluble
Baihong Guo et al.
Neurobiology of aging, 96, 223-232 (2020-10-12)
One major pathological process in Alzheimer's disease is mediated by hyperphosphorylated tau, which includes altered microtubules (MTs) and functions associated with tau. A potential way to compensate for altered MT function is to use an MT stabilizer, such as epothilone
商品
Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.
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