产品名称
脂蛋白,高密度 来源于人类血浆, ≥95% (SDS-PAGE), solution
biological source
human plasma
assay
≥95% (SDS-PAGE)
form
solution
packaging
vial of 10 mg protein
technique(s)
cell culture | mammalian: suitable
functional group
ester
phospholipid
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Gene Information
human ... APOB(338), APOC2(344), APOE(348)
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Biochem/physiol Actions
高密度脂蛋白(HDL)是胆固醇从血液、组织和器官转运到肝脏的转运剂,在肝脏中胆固醇会分解。 这个过程最终有助于清除动脉胆固醇。HDL俗称“好胆固醇”,占人体总胆固醇的20%-30%。
HDL用于心血管研究和开发潜在的心血管风险管理方法。
HDL用于心血管研究和开发潜在的心血管风险管理方法。
Disclaimer
仅供研究使用。本品在法国的科研应用受到监管,包括用于进口和出口活动(法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2)。如《公共卫生法典》所述,购买者(即最终用户)需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
Other Notes
Physical form
含150 mM NaCl和0.01% EDTA的溶液,pH 7.4
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
高风险级别生物产品--人源产品
此项目有
Tisha R Joy
Pharmacology & therapeutics, 135(1), 18-30 (2012-04-03)
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has been associated with a 25-30% reduction in cardiovascular disease risk. However, there still remains a significant and quantifiable risk. Since epidemiologic data have demonstrated that low levels of high-density lipoprotein cholesterol (HDL-C)
Kyung-Hyun Cho
Medicines (Basel, Switzerland), 8(7) (2021-08-07)
The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I
Mark J Cziraky et al.
Journal of managed care pharmacy : JMCP, 14(8 Suppl), S3-28 (2009-11-07)
Most clinicians recognize the importance of reducing low-density lipoprotein cholesterol (LDL-C) and, therefore, address this therapeutic need to decrease cardiovascular disease risk. In addition to the critical role that LDL-C plays, recent studies have shown the contribution of other lipid
Santiago Redondo et al.
Lipids in health and disease, 10, 175-175 (2011-10-12)
Epidemiologic studies indicate a strong inverse correlation between plasma levels of high-density lipoproteins (HDL) and cardiovascular disease (CVD). The most relevant cardioprotective mechanism mediated by HDL is thought to be reverse cholesterol transport (RCT). New insights in HDL biology and
Menno Hoekstra et al.
Current opinion in lipidology, 23(2), 127-132 (2012-01-21)
Scavenger receptor class B type I (BI) is primarily known for its role in the selective uptake of cholesteryl esters from HDL, the final step in reverse cholesterol transport. Here, we will discuss findings that highlight the recently established novel
商品
Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.
Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.
由于胆固醇是水不溶性分子,必须包装后才能在血浆中运输。包装胆固醇、胆固醇酯和甘油三酯以便运输的颗粒称为脂蛋白。
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