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生物来源
bacterial (Salmonella typhosa)
质量水平
无菌性
γ-irradiated
产品线
BioXtra
表单
lyophilized powder
纯化方式
gel-filtration chromatography
技术
cell culture | mammalian: suitable
杂质
<1% Protein (Lowry)
颜色
white to faint yellow
溶解性
water: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
储存温度
2-8°C
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应用
来自鼠伤寒沙门氏菌的脂多糖用于细胞培养和细胞结合应用。在小鼠脾细胞培养物中研究了 LPS 在 TNF-α 和 IL-6 分泌中的作用。它被用来研究炎症反应在多发性硬化中的作用。
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征成分。LPS 及其脂质 A 部分通过 Toll 样受体 4（TLR4）刺激先天免疫系统的细胞，TLR4 是 Toll 样受体蛋白家族的成员，它能识别常见的病原体相关分子模式（PAMP）。
生化/生理作用
脂多糖（LPS）是革兰氏阴性菌细胞壁的特征性成分。LPS及其脂质A部分可通过Toll样受体4（TLR4）刺激先天免疫系统细胞，TLR4是Toll样受体蛋白家族的成员，它能识别常见的病原体相关分子模式（PAMP）。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Joanne L Jones et al.
Brain : a journal of neurology, 133(Pt 8), 2232-2247 (2010-07-28)
Treatment of early relapsing-remitting multiple sclerosis with the lymphocyte-depleting humanized monoclonal antibody alemtuzumab (Campath [registered trade mark]) significantly reduced the risk of relapse and accumulation of disability compared with interferon β-1a in a phase 2 trial [Coles et al., (Alemtuzumab
D N Dao et al.
Infection and immunity, 72(4), 2067-2074 (2004-03-25)
The mycobacterial cell wall component lipoarabinomannan (LAM) has been described as a virulence factor of Mycobacterium tuberculosis, and modification of the terminal arabinan residues of this compound with mannose caps (producing mannosyl-capped LAM [ManLAM]) in M. tuberculosis or with phosphoinositol
Aurélien Godinat et al.
Current protocols in chemical biology, 6(3), 169-189 (2014-09-11)
The great complexity of many human pathologies, such as cancer, diabetes, and neurodegenerative diseases, requires new tools for studies of biological processes on the whole organism level. The discovery of novel biocompatible reactions has tremendously advanced our understanding of basic
Yasuhisa Ano et al.
Nutrients, 11(9) (2019-09-12)
The number of patients with mental illnesses is rapidly increasing, and daily lifestyle is closely associated with the development of symptoms. It is suggested that inflammatory molecules derived from microglia play crucial roles for the pathophysiology of depression. In the
Yasuhisa Ano et al.
Scientific reports, 10(1), 20028-20028 (2020-11-20)
The prevention of age-related cognitive decline and dementia is becoming a high priority because of the rapid growth of aging populations. We have previously shown that hop bitter acids such as iso-α-acids (IAAs) and matured hop bitter acids (MHBAs) activate
商品
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
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