产品名称
脂多糖 来源于肠沙门氏菌 肠炎血清型, γ-irradiated, BioXtra, suitable for cell culture
purified by
gel-filtration chromatography
technique(s)
cell culture | mammalian: suitable
biological source
Salmonella enterica (Serotype enteritidis)
sterility
γ-irradiated
product line
BioXtra
form
lyophilized powder
impurities
<1% Protein (Lowry)
color
white to yellow cast
solubility
water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless
storage temp.
2-8°C
Quality Level
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Application
来自血清型肠炎沙门氏菌的脂多糖可用于细胞培养和细胞结合应用。它被用于研究炎症在神经病理性疼痛和动脉瘤进展中的作用。
脂多糖 (LPS) 是革兰氏阴性菌细胞壁的特征性成分。LPS 及其脂质 A 部分通过 Toll 样受体 4 (TLR4) 刺激天然免疫系统的细胞。
Biochem/physiol Actions
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征组分。LPS及其脂质A部分可通过Toll样受体4（TLR4）刺激细胞的先天免疫系统，Toll样受体4是Toll样受体蛋白家族的成员，其可识别常见的病原体相关分子模式（PAMP）。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Journal of leukocyte biology, 95(2), 313-323 (2013-10-22)
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The ability to assess the function of a range of cytokine, antigen receptor, and Toll-like receptor (TLR) signaling pathways in a range of immune cells could provide a kind of fingerprint of the state of the human immune system. The
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Low level laser irradiation (LLLI) has been shown to reduce inflammation in a variety of clinical situations. We have shown that LLLI (780 nm) increases aortic smooth muscle cell proliferation and matrix protein secretion and modulates activity and expression of
Rosemary Fernandez et al.
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Phosphorylation of tyrosine, serine, and threonine residues is critical for the control of protein activity involved in various cellular events. An assortment of kinases and phosphatases regulate intracellular protein phosphorylation in many different cell signaling pathways. These pathways include T
Ryan Gene Soderquist et al.
Pharmaceutical research, 27(5), 841-854 (2010-03-13)
Interleukin-10 (IL-10) is an anti-inflammatory molecule that has achieved interest as a therapeutic for neuropathic pain. In this work, the potential of plasmid DNA-encoding IL-10 (pDNA-IL-10) slowly released from biodegradable microparticles to provide long-term pain relief in an animal model
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