L7395
脂肪氧化酶 来源于大豆
Type I-B, lyophilized powder, ≥50,000 units/mg solid
别名:
15-脂氧合酶, LOX A, 亚油酸：氧氧化还原酶, 脂氧合酶
Application
大豆酶将使用花生四烯酸作为底物，以亚油酸作为底物的活性约为 15%；花生四烯酸氧化的产物是 12-或 15-过氧化氢花生四烯酸（12-HPETE 或 15-HPETE）。
来自大豆的脂氧合酶已用于：
- 研究2-(α-D-吡喃葡萄糖基)甲基-2,5,7,8-四甲基色胺-6-醇(TMG)对脂蛋白氧化的影响
- 作为脂氧合酶的代表酶，在微孔板检测平台上筛选木材提取物降解酶
- 作为脂氧合酶抑制活性检测的阳性对照品
Biochem/physiol Actions
催化含有顺式，顺式-1,4-戊二烯结构的脂质的氢过氧化。
在接近100℃的温度下热处理5到10分钟，使脂氧合酶失活。研究表明，γ辐射处理降低了大豆脂氧合酶的比活性。这类酶可用于与哮喘和过敏相关的研究。脂氧合酶适用于工业生物转化，如芳香精细化学品的生产。
General description
脂氧化酶(LOX)又名脂氧合酶，是一种非血红素铁蛋白。脂氧合酶在植物、部分微生物和动物中广泛存在。根据pH值和最适温度、底物特异性以及不同试剂的抑制程度，分为LOX-1、LOX-2和LOX-3。
Other Notes
当亚油酸为 3.0 mL 体积（1 cm 光径）底物时，25°C、pH 9.0 条件下 1 个单位每分钟将导致 A 234 增加 0.001。一个 A 234 单位相当于氧化 0.12μ 摩尔亚油酸。
Physical form
含有稳定剂和 NaCl
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
此项目有
Sereyvath Yoeun et al.
Frontiers in chemistry, 6, 500-500 (2018-11-15)
Allene oxide cyclase (AOC) is a key enzyme in the jasmonic acid (JA) biosynthetic pathway in plants, during which it catalyzes stereospecific conversion of 12,13(S)-epoxy-9(Z),11,15(Z)-octadecatrienoic acid (12,13-EOT) to cis(+)-12-oxophytodienoic acid. Here, rice allene oxide cyclase (OsAOC) was localized to the
Norimasa Yoshida et al.
Atherosclerosis, 162(1), 111-117 (2002-04-12)
A novel vitamin E derivative that is freely soluble in water, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG), was evaluated for ability to inhibit development of atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits or cholesterol-loaded New Zealand White rabbits. Although TMG rapidly entered the circulation
Cristina Theoduloz et al.
Chemical biology & drug design, 93(3), 290-299 (2018-10-09)
The aim of this work was to compare the anti-inflammatory activity of compounds prepared from terpenes and the synthetic drugs ibuprofen and naproxen. The anti-inflammatory activity of the hybrid compounds was compared with the activity of the parent compounds. This
Stabilization of Lipoxygenase-1 from Glycine max by Microencapsulation
Lakshmi MC, et al.
Drying Technology, 33(4), 493-501 (2015)
Ewelina Zielińska et al.
Nutrients, 9(9) (2017-09-05)
This study investigated the effect of heat treatment of edible insects on antioxidant and anti-inflammatory activities of peptides obtained by in vitro gastrointestinal digestion and absorption process thereof. The antioxidant potential of edible insect hydrolysates was determined as free radical-scavenging
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