推荐产品
质量水平
检测方案
≥90% (TLC)
形式
powder
颜色
white
应用
detection
储存温度
−20°C
SMILES字符串
C[C@H](O)C(=O)SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
InChI
1S/C13H21N3O8S/c1-6(17)13(24)25-5-8(11(21)15-4-10(19)20)16-9(18)3-2-7(14)12(22)23/h6-8,17H,2-5,14H2,1H3,(H,15,21)(H,16,18)(H,19,20)(H,22,23)/t6-,7-,8-/m0/s1
InChI key
VDYDCVUWILIYQF-FXQIFTODSA-N
应用
- Untargeted metabolomics provide new insights into the implication of Lactobacillus helveticus strains isolated from natural whey starter in methylglyoxal-mediated browning.: This research utilizes untargeted metabolomics to investigate the role of S-lactoylglutathione in the browning reaction mediated by methylglyoxal, highlighting its implications in food processing and safety (Galimberti S et al., 2023).
- Multi-omics analysis reveals the molecular regulatory network underlying the prevention of Lactiplantibacillus plantarum against LPS-induced salpingitis in laying hens.: The study identifies the role of S-lactoylglutathione in the regulatory network that prevents LPS-induced salpingitis, emphasizing its importance in avian health and biotechnology applications (Song D et al., 2023).
- Analysis of Glyoxal- and Methylglyoxal-Derived Advanced Glycation End Products during Grilling of Porcine Meat.: This study examines the formation of advanced glycation end products (AGEs) derived from glyoxal and methylglyoxal, focusing on the role of S-lactoylglutathione in mitigating these reactions during meat grilling (Eggen MD et al., 2021).
生化/生理作用
S-乳酰谷胱甘肽（SLG）用于研究细菌和植物中谷胱甘肽依赖性乙二醛酶系统和 KefGB 钾外排泵。S-乳酰谷胱甘肽也可用于研究癌症中嘧啶从头合成的抑制。
底物
适用于作为乙二醛酶 II 的底物。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
A Klimes et al.
Canadian journal of microbiology, 52(9), 816-822 (2006-11-18)
A glyoxalase I gene homologue (VdGLO1) was identified in the vascular wilt fungus Verticillium dahliae by sequence tag analysis of genes expressed during resting structure development. The results of the current study show that the gene encodes a putative 345
T Pourmotabbed et al.
The Journal of biological chemistry, 261(30), 14240-14244 (1986-10-25)
Formaldehyde dehydrogenases isolated from several different biological sources have been reported to catalyze the NAD+-dependent oxidative acylation of glutathione by methylglyoxal to form S-pyruvylglutathione, suggesting the involvement of this enzyme in the metabolism of methylglyoxal. However, formaldehyde dehydrogenase from bovine
Nathan F Wenzel et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 9(4), 429-438 (2004-04-07)
Cytosolic glyoxalase 2 (GLX2-2) from Arabidopsis thaliana is a metalloenzyme that has been shown to bind a mixture of Zn, Fe, or Mn when produced in cells grown in rich media. In an effort to prepare metal-enriched samples, GLX2-2 was
Ananda Mustafiz et al.
Methods in molecular biology (Clifton, N.J.), 639, 95-118 (2010-04-14)
Glyoxalase system consists of two enzymes glyoxalase I (Gly I) and glyoxalase II (Gly II). Gly I detoxifies methylglyoxal (MG), a cytotoxic byproduct of glycolysis, to S-lactoylglutathione (SLG) where it uses one molecule of reduced glutathione. Subsequently, SLG is converted
Tobias Baumann et al.
Nature immunology, 21(5), 555-566 (2020-04-25)
Regulatory myeloid immune cells, such as myeloid-derived suppressor cells (MDSCs), populate inflamed or cancerous tissue and block immune cell effector functions. The lack of mechanistic insight into MDSC suppressive activity and a marker for their identification has hampered attempts to
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