L5908
Lacto-N-fucopentaose I
from human milk, ≥90% (HPAE/PAD)
别名:
α-L-Fuc (1→2)-β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNFP I
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关于此项目
经验公式（希尔记法）:
C32H55NO25
化学文摘社编号:
分子量:
853.77
UNSPSC Code:
12352201
PubChem Substance ID:
MDL number:
SMILES string
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](CO)O[C@@H](O[C@H]4[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)[C@@H]4O)[C@@H]3NC(C)=O)[C@@H](O)[C@H](O)[C@@H]1O
biological source
human milk
assay
≥90% (HPAE/PAD)
storage temp.
2-8°C
Other Notes
Blood group H-active pentasaccharide.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Andrew Almond et al.
Biochemistry, 43(19), 5853-5863 (2004-05-12)
Fucosylated O- and N-linked glycans are essential recognition molecules in plants and animals. To understand how they impart their functions, through interactions with proteins, requires a detailed analysis of structure and dynamics, but this is presently lacking. In this study
T Yamagata et al.
Biochemical and biophysical research communications, 181(3), 1004-1009 (1991-12-31)
Mouse embryos at implantation stage were stained successfully with lacto-N-fucopentaose I (LNF-I) bearing neoglycoprotein labeled with rhodamine synthesized by us for the first time. The fluorescent neoglycoproteins carrying LNF-II, -III, LND-I, or LNT failed to stain the embryos. The embryo
S Lindenberg et al.
Journal of reproduction and fertility, 83(1), 149-158 (1988-05-01)
Seven oligosaccharides isolated from human milk were tested for their effect in an in-vitro model of mouse blastocyst adhesion and trophoblast outgrowth on endometrial epithelial monolayers. One compound, lacto-N-fucopentaose I (LNF I), produced a significant reduction in the percentage of
S Lindenberg
Danish medical bulletin, 38(5), 371-380 (1991-10-01)
6.1. Attachment and penetration of the uterine epithelium in the human: The present studies describe to our knowledge the only studies of human in vitro attachment of blastocysts to uterine epithelial monolayers. From these studies, using other mammalian species as
Elin Säwén et al.
The journal of physical chemistry. B, 115(21), 7109-7121 (2011-05-07)
The conformational dynamics of the human milk oligosaccharide lacto-N-fucopentaose (LNF-1), α-L-Fucp-(1 → 2)-β-D-Galp-(1 → 3)-β-D-GlcpNAc-(1 → 3)-β-D-Galp-(1 → 4)-D-Glcp, has been analyzed using NMR spectroscopy and molecular dynamics (MD) computer simulations. Employing the Hadamard (13)C-excitation technique and the J-HMBC experiment
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