所有图片(2)
别名:
亮抑酶肽 半硫酸盐, Acetyl-Leu-Leu-Arg-al, N-乙酰基-L-亮氨酰-L-亮氨酰-L-精氨醛 半硫酸盐
线性分子式:
C20H38N6O4 · 1/2H2SO4
推荐产品
生物来源
microbial
质量水平
产品线
BioUltra
检测方案
≥95% (HPLC)
形式
powder
溶解性
H2O: 50 mg/mL
储存温度
−20°C
SMILES字符串
OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O
InChI
1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1
InChI key
CIPMKIHUGVGQTG-VFFZMTJFSA-N
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相关类别
生化/生理作用
丝氨酸和半胱氨酸蛋白酶抑制剂。抑制纤溶酶、胰蛋白酶、木瓜蛋白酶、钙蛋白酶和组织蛋白酶B。不抑制胃蛋白酶、组织蛋白酶A和D、凝血酶或α-糜蛋白酶。有效浓度为10-100 μM.已有许多研究使用亮抑酶肽来预防因听觉过度刺激或耳毒性抗生素庆大霉素引起的听力损失。(耳蜗毛细胞的丧失被认为是由钙蛋白酶介导的。)
分析说明
由于在溶液中形成的互变异构体，亮抑酶肽可在HPLC上形成多个峰。大多数污染肽为外消旋亮抑酶肽。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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