生物来源
Escherichia coli (O26:B6)
质量水平
无菌性
0.2 μm filtered
形式
aqueous solution
浓度
1 mg/mL
颜色
colorless to faint yellow
溶解性
water: soluble
运输
wet ice
储存温度
2-8°C
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一般描述
本品为 0.2 um 过滤水溶液，含 1 mg/mL 来自大肠杆菌血清型 O26：B6 的脂多糖 (LPS)。这种 LPS 血清型已被用于感染性休克研究。
应用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征成分。LPS及其脂质A部分通过Toll样受体4（TLR4）刺激先天免疫系统的细胞，TLR4是Toll样受体蛋白家族的成员，该家族可识别常见的病原体相关分子模式（PAMP）。
生化/生理作用
脂多糖（LPS）位于膜的外层，并且在非包封的菌株中暴露在细胞表面上。它们有助于外膜的完整性，并保护细胞免受胆汁盐和亲脂性抗生素的作用。
制备说明
用于制备溶液的 LPS 经过苯酚提取和凝胶过滤层析纯化。通过苯酚提取制备的脂多糖含有高达 60% 的 RNA 和少于 1% 的蛋白质。随后通过凝胶过滤色谱法进行纯化，可去除苯酚提取的 LPS 中存在的大部分蛋白质，但留下的产物仍含有 10-20% 的核酸。采用离子交换色谱法进一步纯化，得到含 <1% 蛋白质和 <1% RNA 的 LPS 产品。
相关产品
产品编号
说明
价格
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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商品
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
相关内容
Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.
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