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质量水平
检测方案
≥80% (HPLC)
形式
solid
分子量
395.5
溶解性
ethanol: soluble
储存温度
−20°C
SMILES字符串
C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)C=C(C)CCC=C1
InChI
1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
InChI key
NSHPHXHGRHSMIK-JRIKCGFMSA-N
一般描述
拉春库林 B是一种大环毒素,由红海海绵(Latruncula magnifica )产生。
应用
来自红海海绵(Latruncula magnifica )的拉春库林 B在各种实验中用于肌动蛋白解聚。它还被用作骨髓来源树突状细胞 (BMDC)完全培养基中的一种成分,用于研究树突状细胞中吞噬体小管的形成。
生化/生理作用
拉春库林B 在体外抑制肌动蛋白聚合。拉春库林B破坏了微丝介导的过程。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
高风险级别生物产品--病毒,疫苗等
The Journal of cell biology, 205(1), 67-81 (2014-04-09)
The axon initial segment (AIS) of differentiated neurons regulates action potential initiation and axon-dendritic polarity. The latter function depends on actin dynamics, but actin structure and functions at the AIS remain unclear. Using platinum replica electron microscopy (PREM), we have
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Development of the theta comparative cell scoring method to quantify diverse phenotypic responses between distinct cell types
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Visualizing toll-like receptor-dependent phagosomal dynamics in murine dendritic cells using live cell microscopy
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