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Merck
CN

L5152

Sigma-Aldrich

Lewis-X trisaccharide

≥99% (HPLC)

别名:

α-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-D-GlcNAc, Lex Trisaccharide

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About This Item

经验公式(希尔记法):
C20H35NO15
CAS号:
分子量:
529.49
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

方案

≥99% (HPLC)

储存温度

2-8°C

SMILES字符串

CC1OC(OC(C(NC(C)=O)C=O)C(OC2OC(CO)C(O)C(O)C2O)C(O)CO)C(O)C(O)C1O

InChI

1S/C20H35NO15/c1-6-11(27)13(29)15(31)19(33-6)35-17(8(3-22)21-7(2)25)18(9(26)4-23)36-20-16(32)14(30)12(28)10(5-24)34-20/h3,6,8-20,23-24,26-32H,4-5H2,1-2H3,(H,21,25)

InChI key

ZAFUNKXZZPSTLA-UHFFFAOYSA-N

生化/生理作用

Lewis-X is a developmentally regulated antigen and has been suggested to be a tumor marker. At high concentrations, it inhibits P-selectin−mediated adhesion.

其他说明

Lewis-X is the trisaccharide part of the sialyl-Lewis-X tetrasaccharide, the suggested ligand for P- and E-selectins.

法规信息

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历史批次信息供参考:

分析证书(COA)

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Wilkins, W.M., et al.
ACS Symp. Ser., 519, 34-34 (1993)
L A Lasky
Science (New York, N.Y.), 258(5084), 964-969 (1992-11-06)
Although a bewildering array of cell surface carbohydrate structures have been described, the physiological relevance of any of these complex molecules has often eluded biologists. A family of cell surface glycoproteins, the "selectins," has a characteristic ability to use some
Marko Haramija et al.
Rapid communications in mass spectrometry : RCM, 31(20), 1709-1719 (2017-08-15)
Affinity mass spectrometry (AMS) is an emerging tool in the field of the study of protein•carbohydrate complexes. However, experimental obstacles and data analysis are preventing faster integration of AMS methods into the glycoscience field. Here we show how analysis of

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