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一般描述
凝集素是碳水化合物结合蛋白。它们无处不在，常见于真菌、植物和动物体内。该蛋白质的二级结构富含β-链，并且在表面上具有碳水化合物结合位点。
应用
Triticum vulgaris（小麦）来源凝集素已用于：
- 处理转染细胞，以进行免疫荧光分析
- 立体定位注射到小鼠体内，以进行神经元示踪
- 免疫组化，以分析心肌细胞
用于荧光检测含有 β(1→4)-N-乙酰基-D葡糖胺的糖蛋白
生化/生理作用
凝集素在糖缀合物鉴定、成像和靶向过程中发挥着关键作用。它可用于芯片分析，实现有效的糖组图谱分析。在植物和真菌体内，凝集素可防御病原体/寄生物。凝集素在宿主识别和组织粘附中同样发挥主要作用。
WGA 不具有血型特异性，但具有与 N-乙酰基-β-D-葡糖胺残基和 N-乙酰基-β-D-葡糖胺低聚物的亲和性。WGA 不含蛋白结合糖。
包装
基于蛋白含量进行包装。
外形
含有磷酸盐缓冲盐
制备说明
由亲和纯化凝集素制备偶联物。
相关产品
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
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Tissues with high-energy demand including the heart are rich in the energy-producing organelles, mitochondria, and sensitive to mitochondrial dysfunction. While alterations in mitochondrial function are increasingly recognized in cardiovascular diseases, the molecular mechanisms through which changes in mitochondria lead to
Robert H Oakley et al.
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Rui Guo et al.
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Diabetes is a major risk factor for cardiovascular disease and the lysosomal cysteine protease cathepsin K plays a critical role in cardiac pathophysiology. To expand upon our previous findings, we tested the hypothesis that, knockout of cathepsin K protects against
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Peal DS, et al.
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Chandrakumar Balaratnasingam et al.
American journal of ophthalmology, 189, 55-64 (2018-02-23)
To use the capillary-free zone along retinal arteries, a physiologic area of superficial avascularization, as an anatomic paradigm to investigate the reliability of optical coherence tomography angiography (OCTA) for visualizing the deep retinal circulation. Validity analysis and laboratory investigation. Five
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