L4879
Lumiflavine
powder
别名:
7,8,10-Trimethylbenzo[g]pteridine-2,4(3H,10H)-dione, 7,8,10-Trimethylisoalloxazine
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关于此项目
经验公式（希尔记法）:
C13H12N4O2
化学文摘社编号:
分子量:
256.26
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
214-125-5
MDL number:
Beilstein/REAXYS Number:
269756
SMILES string
CN1c2cc(C)c(C)cc2N=C3C(=O)NC(=O)N=C13
form
powder
storage temp.
−20°C
Biochem/physiol Actions
Lumiflavine (Lumiflavin) is produced by the photolysis of vitamin B2 (Riboflavin). Lumiflavine, a riboflavin uptake inhibitor, is used to study riboflavin uptake in intestinal epithelial (Caco-2) and other epithelial cells.
signalword
Warning
hcodes
Hazard Classifications
Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Valeria Bafunno et al.
The Journal of biological chemistry, 279(1), 95-102 (2003-10-14)
We have studied the functional steps by which Saccharomyces cerevisiae mitochondria can synthesize FAD from cytosolic riboflavin (Rf). Riboflavin uptake into mitochondria took place via a mechanism that is consistent with the existence of (at least two) carrier systems. FAD
N B Sankaran et al.
The journal of physical chemistry. B, 113(5), 1522-1529 (2009-01-30)
The binding behavior of lumiflavin, a biologically vital ligand, with DNA duplexes containing an abasic (AP) site and various target nucleobases opposite the AP site is studied. Lumiflavin binds selectively to thymine (T) opposite the AP site in a DNA
Vincent Sichula et al.
The journal of physical chemistry. B, 114(29), 9452-9461 (2010-07-06)
We investigated the oxidation behavior of 5-ethyl-4a-hydroxy-3-methyl-4a,5-dihydrolumiflavin (pseudobase Et-FlOH) in acetonitrile with the aim of determining if the two-electron oxidized Et-FlOH(2+) undergoes a release of hydroxyl cation and the production of 5-ethyl-3methyllumiflavinium cation (Et-Fl(+)). The focus of this work is
Hamid M Said et al.
The Journal of physiology, 566(Pt 2), 369-377 (2005-05-10)
In mammalian cells (including those of the ocular system), the water-soluble vitamin B2 (riboflavin, RF) assumes an essential role in a variety of metabolic reactions and is critical for normal cellular functions, growth and development. Cells of the human retinal
H M Said et al.
The American journal of physiology, 266(1 Pt 1), G15-G21 (1994-01-01)
The cellular and molecular regulation of intestinal absorption of the water-soluble vitamin riboflavine (RF) is poorly understood. The availability of a suitable in vitro cultured system that possesses the transport characteristics of the native intestinal absorptive cells would provide a
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