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Merck
CN

L4777

脂肪酶丙烯酸树脂

greener alternative

≥5,000 U/g, recombinant, expressed in Aspergillus niger

别名:

Novozyme 435

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化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-619-9
MDL number:
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产品名称

脂肪酶丙烯酸树脂, ≥5,000 U/g, recombinant, expressed in Aspergillus niger

InChI key

QWZUIMCIEOCSJF-CHHCPSLASA-N

InChI

1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;

recombinant

expressed in Aspergillus niger

form

solid

specific activity

≥5,000 U/g

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

matrix

macroporous acrylic resin

application(s)

diagnostic assay manufacturing

greener alternative category

storage temp.

2-8°C

Quality Level

相关类别

Application

热稳定脂肪酶固定化制剂,特别适用于酯和酰胺的合成,并具有广泛的底物特异性。
脂肪酶丙烯酸树脂用于:
  • 作为催化剂,用丁酸进行pLACT的酯化反应
  • 作为添加剂,用于全氢化菜籽油(FHCO)和高油酸葵花籽油(HOSO)混合物,进行酶促酯交换
  • 研究其对酯化时油酸转化程度的影响

Biochem/physiol Actions

脂肪酶可用于洗涤剂、食品、皮革、制药和乳品行业。它具有多种特性,例如底物特异性、立体特异性和区域选择性。还参与多种生物转化反应,例如水解、酯化、酸解和氨解。由于因为可用于酯化、水解、氨解和酯交换反应,南极假丝酵母(Candida antarctica )脂肪酶B被认为是一种重要的酶。

General description

我们致力于为您提供更环保的替代产品,以符合“绿色化学的12项原则”的一项或多项原则要求。该产品针对生物柴油研究进行了优化,可提高能效并防止浪费。有关详细信息,请参阅《Biofiles》的文章
脂肪酶属于水解酶类。基于动、植物的微生物主要产生脂肪酶。也可由海洋生物生产。
脂肪酶由一种经过基因改性的黑曲霉( Aspergillus niger )微生物进行深层发酵并吸附在大孔树脂上而制成。

Other Notes

对于相同反应,本品可重复使用。不同反应则不建议重复使用,因为会有交叉污染风险,且活性也可能降低。可重复次数尚未确定。

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What solvents are most compatible with Product L4777, Lipase acrylic resin?

    This resin works well in solvent-free reactions, as well as in inert water immiscible solvents such as petroleum ether, n-hexane and n-heptane. If the reaction being catalyzed is hydrolysis of an ester, addition of water to the reaction mix is recommended. For other reactions water is likely not required, and in some cases would actually be detrimental.

  5. What is the substrate specificity of Product L4777, Lipase acrylic resin?

    Lipase acrylic resin has a broad substrate specificity. It promotes reactions between a wide range of primary and secondary alcohols and carboxylic acids.

  6. What are the components of Product L4777, Lipase acrylic resin, and what are the optimal recommended conditions?

    This product consists of a thermostable lipase enzyme immobilized on a macroporous acrylic bead resin. The bead-shaped particles have a diameter in the range of 0.3-0.9 mm. The resin will be compatible with stearyl alcohol at temperatures of 40-60°C, which is the normal operating temperature of the enzyme. This immobilized enzyme can be used in hexane with no adverse effects.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Marine fungal and bacterial isolates for lipase production: A comparative study
Advances in Food and Nutrition Research, 78, 71-94 (2016)
Hua Zhao et al.
RSC advances, 8(63), 36025-36033 (2018-10-23)
Enzymatic ring-opening polymerization (ROP) is a benign method for preparing polyesters, such as polylactides and other polylactones. These reactions are typically carried out at relatively high temperatures (60-130 °C), however, there is a deficiency of enzyme-compatible solvents for such thermally-demanding
Bartłomiej Zieniuk et al.
Biotechnology letters, 43(3), 601-612 (2020-10-27)
The aim of the study was to evaluate the possibility of using Y. lipolytica biomass as a whole-cell catalyst in the synthesis of lipophilic antioxidants, with the example of esterification of five phenolic acids with 1-butanol. Freeze-dried Y. lipolytica biomass
Covalent immobilization of Candida antarctica lipase B on nanopolystyrene and its application to microwave-assisted esterification
Bukhari A, et al.
Chinese Journal of Catalysis, 35(9), 1555-1564 (2014)
Lipase: An Industrial Enzyme Through Metagenomics (2018)

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