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L4516

脂多糖 来源于大肠杆菌 0127:B8

BioXtra, suitable for cell culture, γ-irradiated

别名:

LPS

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关于此项目

化学文摘社编号:
93572-42-0
UNSPSC Code:
12352211
EC Number:
297-473-0
NACRES:
NA.75
MDL number:
MFCD00212998
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biological source

Escherichia coli (O127:B8)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

form

lyophilized powder

purified by

gel-filtration chromatography

technique(s)

cell culture | mammalian: suitable

impurities

<1% Protein (Lowry)

solubility

H2O: 5 mg/mL, slightly hazy

storage temp.

2-8°C

Application

来自Escherichia coli 0127:B8脂多糖用于：
  • 研究LPS诱导小鼠巨噬细胞存活
  • 诱导牛PBMC分泌细胞因子
  • 研究LPS诱导促炎环境高易感巨噬细胞细胞凋亡。
  • 进行BV2和BV2-LC3细胞自吞噬实验。
  • 激活人单核细胞，巨噬细胞和小鼠小胶质细胞
  • 诱导293T细胞穿透素-3
脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式（PAMP）的Toll样受体蛋白家族成员Toll样受体4（TLR4）刺激先天性免疫系统细胞。

Biochem/physiol Actions

脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS和它的脂质A单体通过Toll样受体4（TLR4）激活天然免疫系统细胞。作为免疫原抗原，它增强了对于可溶性抗原的免疫反应。

Preparation Note

脂多糖以经γ-射线处理的冻干粉形式提供。如需重悬，可将1 ml无菌的平衡盐溶液或组织培养基加入至小瓶（1 mg）中并轻轻晃动直至粉末溶解。重悬后的产品可采用无菌的平衡盐溶液或组织培养基进一步被稀释至所需的工作浓度。

Other Notes

为了全面了解我们针对客户研究提供的各种脂多糖产品，建议您访问我们的碳水化合物分类页面。

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000473302
0000473302
0000370464
0000370464
0000242816

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全球贸易项目编号

货号GTIN
L4516-1MG04061833957578