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安全信息

L3908

Sigma-Aldrich

β-乳球蛋白 来源于牛奶

≥90% (PAGE), lyophilized powder

别名:

βLg, BLG, Bos d 5, beta-lactoglobulin

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About This Item

CAS号:
9045-23-2
EC 号:
232-928-9
MDL编号:
MFCD00130635
UNSPSC代码:
12352202
NACRES:
NA.61

生物来源

bovine milk

质量水平

300

检测方案

≥90% (PAGE)

形式

lyophilized powder

技术

ELISA: suitable

UniProt登记号

P02754

储存温度

2-8°C

基因信息

bovine ... LGB(280838)

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一般描述

来自奶牛的牛奶含有β-乳球蛋白（BLG）。它天然存在许多遗传变异体，最普遍的牛变异体是BLG A和BLG B。

应用

β-乳球蛋白被用于细胞学检测，以诊断肠易激综合征患者的食物超敏反应。

生化/生理作用

βLg是脂质运载蛋白家族的成员，它是由162个氨基酸组成的小分子蛋白，分子量约为18,400Da。它具有由八条链组成的β桶状结构（A-H链），桶外存在一个具有三个转角的a螺旋和第九条β链（I链），其形成二聚体形成界面的一部分。

其他说明

含 β-乳球蛋白 A 和 B，可通过色谱法分离。

质量

可能不含叶酸结合蛋白；不推荐用于叶酸分析。

制备说明

色谱纯化产品

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

动植物源性产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

  2. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  3. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  4. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. What is the molecular weight of Product L3908, β-Lactoglobulin from bovine milk?  

    Product L3908, β-Lactoglobulin from bovine milk, exists as a dimer of two peptides. Peptide A = 18,367, B = 18,281; the monomer is approximately 36,600.

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Sirpa Jylhä et al.
Journal of immunological methods, 350(1-2), 63-70 (2009-08-04)
Cow's milk allergy (CMA) is a common food allergy, especially among infants and young children. Approximately 85% of milk-allergic children outgrow their allergy by the age of three but the remaining 15% remain allergic. Bovine beta-lactoglobulin (BLG) is one of
Lena Wartosch et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(12), 4056-4068 (2009-08-08)
Mutations in either ClC-7, a late endosomal/lysosomal member of the CLC family of chloride channels and transporters, or in its beta-subunit Ostm1 cause osteopetrosis and lysosomal storage disease in mice and humans. The severe phenotype of mice globally deleted for
Tilman Barz et al.
Journal of chromatography. A, 1217(26), 4267-4277 (2010-05-07)
In this work, parameters of the steric mass-formalism SMA are optimally ascertained for a reliable determination of the adsorption isotherms of beta-lactoglobulin A and B under non-isocratic conditions. For this purpose, static batch experiments are used in contrast to the
Jonathan Vaneyck et al.
The Journal of biological chemistry, 296, 100358-100358 (2021-02-05)
The aggregation of the protein α-synuclein (aSyn) into amyloid fibrils in the human brain is associated with the development of several neurodegenerative diseases, including Parkinson's disease. The previously observed prion-like spreading of aSyn aggregation throughout the brain and the finding
Junzhen Zhong et al.
Food chemistry, 278, 491-496 (2018-12-26)
Previous work indicated that conformational changes of β-lactoglobulin (β-LG) induced by dynamic high pressure microfluidization (DHPM) was related to the increase of antigenicity. In this study, β-LG glycated with 1-kestose and combined with DHPM decreased the antigenicity of β-LG. The
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