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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white
溶解性
H2O: soluble 20 mg/mL
创始人
Merck & Co., Inc., Kenilworth, NJ, U.S.
储存温度
−20°C
SMILES字符串
Cl.Cc1ccccc1N2CCN(CC2)S(=O)(=O)C[C@]34CC[C@H](C[C@@H]3NC(=O)[C@@H](N)CCS(C)(=O)=O)C4(C)C
InChI
1S/C26H42N4O5S2.ClH/c1-19-7-5-6-8-22(19)29-12-14-30(15-13-29)37(34,35)18-26-11-9-20(25(26,2)3)17-23(26)28-24(31)21(27)10-16-36(4,32)33;/h5-8,20-21,23H,9-18,27H2,1-4H3,(H,28,31);1H/t20-,21+,23+,26-;/m1./s1
InChI key
GIUFQWFJHXXXEQ-SWJTYIIKSA-N
基因信息
human ... OXTR(5021)
生化/生理作用
L-368,899是一种非肽催产素受体(OTR)拮抗剂。
特点和优势
该化合物由Merck & Co., Inc.(美国新泽西州Kenilworth)开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单, 请单击此处。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Ling Huang et al.
Brain research bulletin, 166, 161-171 (2020-12-07)
Social experiences during early life are thought to be critical for proper social and emotional development. Conversely, social insults during development causes long-lasting behavioral abnormalities later in life. However, how juvenile social deprivation influences social and emotional behaviors remains poorly
Marianna Leonzino et al.
Hormones and behavior, 114, 104543-104543 (2019-06-21)
Long-standing studies established a role for the oxytocin system in social behavior, social reward, pair bonding and affiliation. Oxytocin receptors, implicated in pathological conditions affecting the social sphere such as autism spectrum disorders, can also modulate cognitive processes, an aspect
Vimala N Bharadwaj et al.
Pharmaceutics, 16(6) (2024-06-27)
Following a mild traumatic brain injury (mTBI), the most prevalent and profoundly debilitating occurrence is the emergence of an acute and persistent post-traumatic headache (PTH), for which there are presently no approved treatments. A crucial gap in knowledge exists regarding
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